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Fig. 10 | Orphanet Journal of Rare Diseases

Fig. 10

From: Alpha-lipoic acid supplementation corrects pathological alterations in cellular models of pantothenate kinase-associated neurodegeneration with residual PANK2 expression levels

Fig. 10

Effect of α-LA treatment on carbonylated protein levels. Control and PKAN fibroblasts (P1, P2, P3) were treated with α-LA at 10 μM for 20 days. a A representative image of carbonylated protein content in treated and untreated control and PKAN fibroblasts by Oxyblot Protein Oxidation Kit b Oxyblot quantification by ImageJ. Data represent the mean ± SD of three separate experiments. **p < 0.005 ***p < 0.001 between PKAN patients and controls. ##p < 0.005 between untreated and treated fibroblasts. A.U., arbitrary units

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Orphanet Journal of Rare Diseases

ISSN: 1750-1172