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Table 1 Quality appraisal of included papers

From: How do patients and other members of the public engage with the orphan drug development? A narrative qualitative synthesis

 

1. Clear statement of aims?

2. Appropriate methodology?

3. Research design appropriate?

4. Recruitment strategy appropriate

5. Data collection address the research issue?

6. Relationship between researcher and participant?

7. Ethical issues taken into consideration?

8. Data Analysis sufficiently rigorous?

9. Is there a clear statement of findings?

10. Value of the research

Bendixen et al. [33]

Y

Y

Y

Y

Y

N

Y

CNT

CNT

Y

Carroll et al. [7]

Y

Y

Y

Y

Y

N

Y

CNT

CNT

Y

Gaasterland et al. [42]

Y

Y

N

N

CNT

Y

CNT

CNT

CNT

Y

Gaasterland et al. [43]

Y

CNT

Y

Y

Y

N

Y

CNT

CNT

Y

Gengler [35]

Y

Y

Y

Y

Y

Y

CNT

.Y

Y

Y

Kesselheim et al. [36]

Y

Y

Y

Y

CNT

N

CNT

CNT

Y

Y

Lopes et al. [44]

Y

Y

Y

N

N

N

Y

N

N

Y

Li et al. [45]

Y

Y

Y

N

N

N

Y

N

N

Y

Menon et al. [38]

Y

Y

Y

Y

Y

N

Y

N

CNT

Y

Peay et al. [37]

Y

Y

Y

Y

Y

N

CNT

N

CNT

Y

Tingley et al. [39]

Y

Y

Y

CNT

Y

N

Y

Y

Y

Y

Tingley et al. [40]

Y

Y

Y

CNT

Y

N

Y

Y

Y

Y

Young et al. [41]

Y

Y

Y

CNT

Y

N

Y

Y

CNT

Y

  1. Key: Y, Yes; N, No; CNT could not tell