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Box 1 Summary of topic guide

From: “I just wanted to speak to someone- and there was no one…”: using Burden of Treatment Theory to understand the impact of a novel ATMP on early recipients

Background information:

 Age, time since diagnosis

What did you understand of CAR-T therapy and the treatment process?

 What information was provided by care staff?

 Did you access information independently? Where from?

What conversations did you have about its suitability and potential use?

 Were side-effects discussed?

 What was the decision-making process like?

What was your experience of the treatment process?

 Who was involved, where?

 Were there any side-effects?

 What were their impact?

 What were you told of your progress?

What were your experiences subsequent to receiving the treatment?

 Level of service utilisation (follow-up, unplanned admissions etc.)

 Side-effects

What support was available?

 Where from? (NHS or others?)