Increasing incidence rate of breast cancer in cystic fibrosis - relationship between pathogenesis, oncogenesis and prediction of the treatment effect in the context of worse clinical outcome and prognosis of cystic fibrosis due to estrogens

Table 1 An overview of epidemiological studies among CF patients

Study	Country of origin	Study period	No. CF patients	No. cases of all cancer types	No. breast cancer
Neglia JP	USA, CAN, EU*	1982–1994	> 46,511	82	2
Garcia FU	USA	1971–1997	19	unobserved	3
Johannesson M	SWE	1968–2003	884	41	0
Maisonneuve P	USA	1990–2009	41,188	172	15
Archangelidi O	GBR	2009–2017	12,886	146	13
Appelt D	AUT	1995–2019	229	11	0

Legend: USA: The United States of America, CAN: Canada, EU: European Union, SWE: Sweden, GBR: The United Kingdom of Great Britain and Northern Ireland, AUT: Austria
* Austria, Belgium, Denmark, France, Finland, Germany, Hungary, Iceland, Ireland, Italy, The Netherlands, Norway, Romania, Spain, Sweden, Switzerland, UK

ISSN: 1750-1172