Table 5 Binary logistic regression for SIRT1 rs3818292, rs3758391, between females of ON and control groups
Polymorphism | Model | Genotype | OR (95%. CI) | p-value | AIC |
|---|---|---|---|---|---|
rs3818292 | Codominant | A/A | 1 | 0.272 1 | 225.119 |
A/G | 1.561 (0.705–3.455) | ||||
G/G | – | ||||
Dominant | A/A | 1 | 0.322 | 224.006 | |
A/G + G/G | 1.490 (0.677–3.280) | ||||
Recessive | AA + A/G | 1 | 1 | 224.294 | |
G/G | – | ||||
Overdominant | A/A + G/G | 1 | 0.262 | 223.741 | |
A/G | 1.575 (0.712–3.485) | ||||
Additive | G | 1.379 (0.648–2.937) | 0.405 | 224.285 | |
rs3758391 | Codominant | C/C | 1 | 0.020 0.526 | 221.480 |
C/T | 2.198 (1.130–4.277) | ||||
T/T | 1.592 (0.379–6.690) | ||||
Dominant | C/C | 1 | 0.023 | 219.682 | |
C/T + T/T | 2.122 (1.109–4.060) | ||||
Recessive | C/C + C/T | 1 | 0.905 | 224.948 | |
T/T | 1.089 (0.271–4.377) | ||||
Overdominant | C/C + T/T | 1 | 0.025 | 219.862 | |
C/T | 2.096 (1.100–3.995) | ||||
Additive | T | 1.684 (0.995–2.849) | 0.052 | 221.181 | |
rs7895833 | Codominant | A/A | 1 | 0.006 0.593 | 218.788 |
A/G | 2.619 (1.312–5.230) | ||||
G/G | 0.556 (0.064–4.798) | ||||
Dominant | A/A | 1 | 0.017 | 219.336 | |
A/G + G/G | 2.255 (1.156–4.399) | ||||
Recessive | AA + A/G | 1 | 0.415 | 224.157 | |
G/G | 0.410 (0.048–3.492) | ||||
Overdominant | A/A + G/G | 1 | 0.005 | 217.111 | |
A/G | 2.687 (1.352–5.340) | ||||
Additive | G | 1.627 (0.933–2.837) | 0.086 | 222.068 |