Table 4 Binary logistic regression for SIRT1 rs3818292, rs3758391, between males of ON and control groups
Polymorphism | Model | Genotype | OR (95%. CI) | p-value | AIC |
|---|---|---|---|---|---|
rs3818292 | Codominant | A/A | 1 | 0.115 1 | 123.561 |
A/G | 2.721 (0.784–9.443) | ||||
G/G | – | ||||
Dominant | A/A | 1 | 0.354 | 125.135 | |
A/G + G/G | 1.732 (0.542–5.531) | ||||
Recessive | AA + A/G | 1 | 1 | 123.901 | |
G/G | – | ||||
Overdominant | A/A + G/G | 1 | 0.098 | 123.358 | |
A/G | 2.857 (0.824–9.906) | ||||
Additive | G | 1.134 (0.455–2.825) | 0.788 | 125.881 | |
rs3758391 | Codominant | C/C | 1 | 0.163 0.715 | 125.976 |
C/T | 1.950 (0.763–4.982) | ||||
T/T | 1.309 (0.308–5.564) | ||||
Dominant | C/C | 1 | 0.202 | 124.228 | |
C/T + T/T | 1.786 (0.733–4.353) | ||||
Recessive | C/C + C/T | 1 | 0.939 | 125.945 | |
T/T | 0.949 (0.244–3.689) | ||||
Overdominant | C/C + T/T | 1 | 0.173 | 124.106 | |
C/T | 1.844 (0.764–4.450) | ||||
Additive | T | 1.326 (0.714–2.460) | 0.371 | 125.162 | |
rs7895833 | Codominant | A/A | 1 | 0.049 1 | 121.054 |
A/G | 2.547 (1.005–6.459) | ||||
G/G | – | ||||
Dominant | A/A | 1 | 0.152 | 123.941 | |
A/G + G/G | 1.936 (0.784–4.781) | ||||
Recessive | AA + A/G | 1 | 1 | 122.844 | |
G/G | – | ||||
Overdominant | A/A + G/G | 1 | 0.031 | 121.416 | |
A/G | 2.779 (1.099–7.028) | ||||
Additive | G | 1.267 (0.614–2.611) | 0.522 | 125.551 |