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Table 5 Association of Population Characteristics with Prevalence of Duchenne/Becker Muscular Dystrophy1, MD STARnet Expanded Surveillance Pilot, 2007–2011

From: Sources of variation in estimates of Duchenne and Becker muscular dystrophy prevalence in the United States

 

Prevalence Rate Ratio

95% Confidence Interval

P-value

Age (years)

Under 5

0.504

0.366–0.686

 < 0.001

 5 to 9

0.901

0.690–1.174

0.427

 10 to 14

Ref.

  

 15 to 19

0.994

0.775–1.275

0.959

 20 to 24

0.732

0.558–0.957

0.020

 25 + 

0.170

0.115–0.250

 < 0.001

State

 Arizona

Ref.

  

 Colorado

1.164

0.786–1.721

0.444

 Iowa

1.368

0.930–2.001

0.086

 New York

2.164

1.620–2.875

 < 0.001

Race/Ethnicity

 Black

0.501

0.301–0.785

0.004

 Hispanic

0.882

0.716–1.081

0.233

 Other

1.424

1.077–1.856

0.009

 White

Ref.

  

 Average number of ascertainment sources2

1.095

0.735–1.629

0.650

 Proportion diagnosed by genetic testing3

1.009

0.533–1.915

0.993

 Proportion treated at MD clinic14

2.696

0.905–8.164

0.073

  1. 1The dependent variable was number of Duchenne and Becker muscular dystrophy cases, with the logarithm of stratum population used as an offset variable
  2. 2Average number of reporting sources for each patient in stratum
  3. 3Proportion of cases diagnosed by genetic testing in the index case or a family member
  4. 4Proportion of patients within stratum that were treated at a muscular dystrophy clinic