Table 2 Clinical effectiveness of BPA during ITI therapy of patients with severe haemophilia A by treatment type
Clinical effectiveness | Outcomes during ITI alongside BPA | Outcomes during BPA only | ||||||
|---|---|---|---|---|---|---|---|---|
BPA treatment type | Total | Statistical significance | BPA treatment type | Total | Statistical significance | |||
Prophylactic (n = 31) | On-demand (n = 13) | n = 44 | p-value* (< 0.05) | Prophylactic (n = 31) | On-demand (n = 13) | n = 44 | p-value* (< 0.05) | |
Bleeding events (any type and of any severity), mean ± SD | 1.5 ± 1.5 | 1.2 ± 0.8 | 1.4 ± 1.3 | 0.830 | 3.4 ± 5.5 | 1.4 ± 0.8 | 2.8 ± 4.7 | 0.191 |
Joint bleeding events (of any severity), mean ± SD | 1.3 ± 1.8 | 1.1 ± 0.8 | 1.2 ± 1.6 | 0.746 | 2.5 ± 4.2 | 1.2 ± 0.8 | 2.1 ± 3.6 | 0.631 |