Fig. 2

Surgical burden by age at time of event. Each patient may have had several surgeries reported across their lifespan and may therefore be included in multiple age subgroups. Event rates per 100 person-years were calculated as the number of events divided by the total number of patient historical years multiplied by 100. ‘Other’ surgeries were those not pre-defined in the CRF used to record data, and mainly consisted of other orthopaedic procedures (e.g., medical device removal, osteotomy, epiphysiodesis)