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Table 1 Characteristics of study participants with achondroplasia (n = 40)

From: Fat infiltration in the thigh muscles is associated with symptomatic spinal stenosis and reduced physical functioning in adults with achondroplasia

Variables

Spinal stenosis

(n = 25)

No stenosis

(n = 15)

Mean difference (95% CI)

P value

Mean (SD)

Mean (SD)

Age, years

44.5 (16.2)

24.4 (7.8)

20.1 (12.4 to 27.9)

 < 0.01

Body mass index, kg/m2

35.5 (6.2)

29.6 (5.2)

5.9 (2.1 to 9.8)

 < 0.01

Height, cm

135.2 (9.6)

132.5 (7.4)

2.8 ( − 3.1 to 8.6)

0.35

Sitting height, cm

86.9 (4.5)

86.4 (2.7)

0.5 ( − 1.9 to 2.8)

0.68

6MWT, m a

392 (123)

523 (61)

 − 131 ( − 192 to  − 70)

 < 0.01

30sSTS, stands b

20.8 (5.6)

26.6 (4.2)

 − 5.7 ( − 9.2 to  − 2.2)

 < 0.01

Activity level, MET c

2284 (2275)

3678 (2825)

 − 1395 ( − 3111 to 321)

0.11

 

% (n)

% (n)

  

Male gender

48 (12)

53 (8)

 − 5 ( − 43 to 32)

1.0

Lower limb extension, yes

28 (7)

20 (3)

8 ( − 24 to 40)

0.85

Wheelchair users

56 (14)

27 (4)

29 ( − 5 to 64)

0.14

  1. aSix-minute walk test (in metres); n = 38 (stenosis group: n = 24; non-stenosis group: n = 14)
  2. b30-second sit-to-stand test (number of full stands); n = 38 (stenosis group: n = 24; non-stenosis group: n = 14)
  3. cMET: metabolic equivalent; n = 37 (stenosis group: n = 23; non-stenosis group: n = 14)