Table 2 Lung function test results at start of mechanical ventilation (= intercept) and average annual change in the years prior to start mechanical ventilation (= slope)
Lung function test (LFT) | SMA type | n (obs) | Annual change LFT (SE) | 95% CI | LFT at start MV (SE) | 95% CI |
|---|---|---|---|---|---|---|
Standardized FVC (%) | Total group | 37 (260) | − 1.75 (0.45) | − 2.66; − 0.86 | 28.84 (2.69) | 23.48; 34.17 |
1c | 7 (69) | − 0.24 (0.94) | − 1.99; 1.53 | 23.69 (6.03) | 12.19; 34.99 | |
2a | 20 (146) | − 2.34 (0.58) | − 3.42; − 1.26 | 27.57 (3.54) | 20.89; 34.27 | |
2b | 7 (40) | − 1.70 (0.94) | − 3.49; 0.06 | 37.82 (5.93) | 26.80; 49.27 | |
3a | 3 (5) | − 2.31 (2.40) | − 6.81; 2.19 | 31.40 (9.29) | 13.78; 49.03 | |
Standardized FEV1 (%) | Total group | 38 (385) | − 1.72 (0.34) | − 2.40; − 1.04 | 28.82 (2.44) | 23.99; 33.69 |
1c | 8 (74) | − 0.27 (0.72) | − 1.62; 1.09 | 26.10 (5.31) | 15.96; 36.15 | |
2a | 20 (243) | − 1.95 (0.43) | − 2.76; − 1.15 | 27.79 (3.24) | 21.67; 33.99 | |
2b | 7 (47) | − 2.15 (0.78) | − 3.62; − 0.67 | 36.40 (5.79) | 25.65; 47.73 | |
3a | 3 (21) | − 2.63 (1.26) | − 5.01; − 0.25 | 30.72 (8.56) | 14.41; 47.01 | |
Standardized PEF (%) | Total group | 20 (247) | − 1.65 (0.46) | − 2.59; − 0.71 | 29.96 (3.31) | 23.35; 36.67 |
1c | 5 (60) | − 0.64 (0.89) | − 2.40; 1.11 | 33.88 (6.75) | 20.78; 47.16 | |
2a | 15 (187) | − 1.99 (0.51) | − 3.00; − 0.97 | 28.71 (3.91) | 21.12; 36.38 | |
PEmax (cmH2O) | Total group | 32 (279) | − 0.03 (0.34) | − 0.78; 0.66 | 35.30 (2.97) | 29.41; 41.36 |
1c | 6 (55) | 0.02 (0.86) | − 1.58; 1.62 | 25.21 (6.44) | 13.22; 37.36 | |
2a | 17 (175) | 0.17 (0.44) | − 0.74; 0.99 | 36.40 (3.89) | 29.08; 43.72 | |
2b | 6 (37) | − 0.35 (0.83) | − 1.93; 1.19 | 41.63 (7.61) | 27.43; 55.99 | |
3a | 3 (12) | − 0.13 (1.95) | − 3.85; 3.52 | 40.03 (11.68) | 17.92; 61.99 |