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Table 3 Gastrointestinal symptoms, feeding issues and medications at pre-baseline, during the short-term evaluation (28 days) and extended follow-up (12 months)

From: Phenylalanine free infant formula in the dietary management of phenylketonuria

 

Pre-baseline (n = 10)

Short-term a (28 days, n = 10)

Long-term (12 months, n = 7)

Gastrointestinal symptoms (n, %)

 Constipation

7 (70%)

6 (60%)

0 (0%)

 Colic

5 (50%)

3 (30%)

1 (14%)

 Vomiting

3 (30%)

3 (30%)

2 (29%)

Stool consistency (n, %)

 Soft

6 (60%)

8 (80%)

N/A

 Loose

4 (40%)

1 (10%)

N/A

 Hard

0 (0%)

1 (10%)

N/A

Poor feeding (n, %)

5 (50%)

3 (30%)

1 (14%)

Medications (n, %)

   

 Laxatives

2 (20%)

2 (20%)

0 (0%)

 Colic treatment

2 (20%)

1 (10%)

0 (0%)

 Antacids/antiemetics

1 (10%)

1 (10%)

1 (14%)

  1. N/A, does not apply
  2. aOne infant who discontinued the study formula at day 14 (subject 1) had a daily diary during the first 14-day and was included in the analysis