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Table 7 Cross-sectional summary statistics, by age group

From: Patient-reported outcomes measures of X-linked hypophosphataemia participants: findings from a prospective cohort study in the UK

Overall instrument score

Total sample

Age: < 40 years

Age: 40–60 years

Age: > 60 years

ANOVA

P-value

Range of submission dates

n

Mean

SD

Median

n

Mean

SD

Median

n

Mean

SD

Median

Health related quality of life

         

EQ-5D-5L (VT) Index score

07/2014–08/2019

19

0.643

0.294

0.728

18

0.708

0.220

0.760

11

0.570

0.302

0.649

0.411

EQ5D VAS score

07/2014–08/2019

19

63.42

26.58

74.00

18

67.22

23.17

68.00

11

53.09

28.10

55.00

0.358

EQ5D-3L (CW) Index score

07/2014–08/2019

19

0.558

0.326

0.664

18

0.604

0.241

0.663

11

0.465

0.345

0.567

0.490

SF-36- physical component score

07/2014–08/2019

18

35.55

15.10

35.88

16

32.01

14.77

28.86

10

28.55

11.46

28.94

0.455

SF-36- mental component score

07/2014–08/2019

18

47.77

9.94

49.28

16

46.23

11.74

46.64

10

52.91

8.39

54.26

0.273

Fatigue

         

FSS score

09/2018–08/2019

7

28.57

11.30

25.00

10

34.60

17.16

32.50

6

34.83

12.12

33.50

0.651

FACIT-F score

04/2015–08/2019

18

104.33

30.51

102.33

16

100.92

28.37

108.00

9

110.67

30.90

108.00

0.737

FACIT-F- physical well-being

04/2015–08/2019

18

18.67

6.89

20.00

16

18.31

6.52

20.50

10

18.67

5.40

20.00

0.986

FACIT-F- social well-being

04/2015–08/2019

18

21.22

4.81

23.00

16

19.10

5.07

19.50

10

21.78

5.83

22.17

0.346

FACIT-F- emotional well-being

04/2015–08/2019

18

15.06

4.78

14.50

16

15.81

4.69

16.00

10

17.22

4.50

17.00

0.454

FACIT-F- functional well-being

04/2015–08/2019

18

18.33

5.24

17.50

16

17.63

5.14

17.50

10

18.89

6.84

19.00

0.806

FACIT-F- fatigue subscale

04/2015–08/2019

18

31.06

13.99

32.50

16

30.06

13.37

34.00

9

34.11

12.77

33.00

0.769

Pain

         

SF-MPQ-2 score

07/2014–08/2019

19

1.89

1.55

1.91

16

2.01

1.72

1.50

11

1.89

1.25

1.86

0.968

Pain detect score

07–2014-08/2019

18

7.89

5.14

8.00

15

8.67

7.17

7.00

10

12.70

5.93

15.50

0.133

Sleep

         

ESS score

09/2018–08/2019

7

5.00

3.00

5.00

10

5.40

3.17

6.00

6

7.67

5.05

7.00

0.389

PSQI score

07/2014–06/2019

18

8.11

5.05

7.00

14

9.64

3.56

10.50

9

9.22

2.77

9.00

0.570

Mental wellbeing

          

HADS anxiety score

04/2015–06/2019

16

6.38

4.56

6.50

15

6.00

3.91

5.00

10

6.10

2.56

6.00

0.963

HADS depression score

04/2015–06/2019

16

4.31

3.52

4.50

15

4.73

3.13

4.00

10

5.30

4.19

4.50

0.789

  1. The sample is the first submitted instrument from each participant
  2. EQ-5D-5L (3L), EuroQol 5 dimensions-5 levels (3 levels); VAS, Visual analogue scale; SF-36, Short-form 36; PCS, Physical Component Score; MCS, Mental Component Score; FSS, Fatigue Severity Scale; ESS, Epworth Sleepiness scale; PSQI, Pittsburgh sleep quality index; FACIT-F, Functional assessment of chronic illness therapy-fatigue; SF-MPQ-2, Short form McGill pain questionnaire version 2; HADS, Hospital anxiety and depression scale