Fig. 3

Neuropathological findings in diprosopus case 2—Top view of the brain, showing alobar holoprosencephaly (HPE) of the left forebrain (L) and lobar HPE with incomplete interhemispheric fissure (↱) of the right forebrain (R), and also internal hydrocephaly (H) (a); basal view of the cerebrum associated with the right cebocephalic face, presenting lobar HPE (R) with incomplete interhemispheric fissure (↰), anterior encephalocele (E) and a single cerebellum (C). (b); skull base presenting duplicated 2 anterior cranial fossae (Fa) with only a single left ethmoidal crest (↘) in the presence of two, left and right olfactorial canals. The 2 pituitary grooves are fused and cleft in the depth (↓↑), thus enabling prolaps of a frontal encephalocele. There is one optic fossa on each side of the fused pituitary grooves (→ ←), the left one showing cross section of one optic nerve and the right one harboring two optic nerves. There are normal two middle (Fm) and one posterior cranial fossae (Fp) (c)