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Fig. 2 | Orphanet Journal of Rare Diseases

Fig. 2

From: Brain malformations in diprosopia observed in clinical cases, museum specimens and artistic representations

Fig. 2

Pathological findings in diprosopus case 3. Female fetus at 18 weeks showing diprosopus tetrophthalmus with median microphthalmic eye bulbs and a single median ear pit (a); X-ray showing mandibular duplication, splicing of the cervical spine and duplication of thoracic vertebral bodies T1-T7 (b); basal view of the duplicated right (R) and left (L) forebrain with two hemispheres each and a single cerebellum ( ←) (c); skull base presenting duplication of frontal fossa (Fa) with two ethmoidal crests, two pituitary fossae ( ↔), each with 2 optic nerves, and a clival cleft () (d); histologic section of the thoracic spinal cord showing incomplete dimyelia with two central canals and two ventral fissurae medianae (→ ←) (e)

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