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Table 1 Audit of ophthalmologic management practices during the chronic phase of epidermal necrolysis: Response from 11 ophthalmologists

From: Ocular sequelae of epidermal necrolysis: French national audit of practices, literature review and proposed management

Treatments

Responses (n = 11)

Artificial tears

10 (91)

 Systematic

7/10 (70)

 Sometimes

3/10 (30)

 Preservative-free

10/10 (100)

Vitamin A Ointment

11 (100)

 Systematic

6/11 (55)

 Sometimes

5/11 (45)

Antiseptic or antibiotic eye drops

8 (73)

 Systematic

0/8 (0)

 Sometimes

8/8 (100)

Antibiotic-corticosteroid eye drops

7 (64)

 Systematic

0/7 (0)

 Sometimes

7/7 (100)

Cyclosporine eye drops

11 (100)

 Systematic

1/11 (9)

 Sometimes

10/11 (91)

Tacrolimus eye drops

4 (36)

 Systematic

0/4 (0)

 Sometimes

4/4

Autologous serum eye drops 20%

6 (55)

 Systematic

0/6 (0)

 Sometimes

6/6 (100)

Systemic immunosuppressants

0

Removal of trichiatic eyelashes

 

 By the ophthalmologist only

10/11 (91)

 By the patient

3/11 (27)

 By ciliary electrolysis

5/11 (45)

 By argon laser

7/11 (64)

Removal of symblepharons

8/10 (80)

 Systematic

0

 Depending on the context

10/10 (100)

 If difficulty fitting SL

8/10 80

 If severe eyelid malposition

9/10 (90)

  + AMT or OMT

7/10 (70)

Corneal ulcer

 Amniotic membrane transplant

9 (82)

 Corneal transplant

6 (55)

In case of meibomian gland dysfunction

 Eyelid hygiene

11 (100)

 Systematic

5/11 (45)

 Sometimes

6/11 (55)

Local antibiotics

10/11 (91)

 Systematic

0

 Sometimes

10/10

General antibiotics

8/11 (73)

 Systematic

0

 Sometimes

8/8 (100)

Indication for scleral lenses

 

 For disabling keratoconjunctivitis

10/10 (100)

 For functional discomfort + visual impact

9/10 (90)

Anti-VEGF (corneal neovascularization)

7/11 (64)

 Subconjunctival

6/7 (86)

 Amniotic membrane transplant

0/7 (0)

 Eye drops

2/7 (29)

  1. AMT Amniotic membrane transplant, OMT Oral mucosa transplant, SL scleral lenses, VEGF vascular endothelial growth factor