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Table 1 Main clinical characteristics of the ECD population (n = 32)

From: Psychiatric disorders, personality and neuropsychological alterations in Erdheim-Chester disease

 

n (%)

BRAF V600E mutation

20 (62.5)

Age at first symptoms (mean[SD])

49.6 [14.2]

Current treatment

Steroid

6 (18.8)

Interferon alpha

2 (6.3)

Vemurafenib

12 (37.5)

Cobimetinib

4 (12.5)

Others

5 (15.6)

Past treatment

Steroid

13 (40.6)

Interferon alpha

24 (75)

Vemurafenib

12 (37.5)

Cobimetinib

7 (21.9)

Others

13 (40.6)

Cerebral MRI patterns*

MRI considered as normal

8 (25)

Tumoral patterns

19 (59.4)

Pseudo-degenerative patterns

15 (46.9)

Vascular patterns

7 (21.9)

  1. ECD Erdheim-Chester disease
  2. *MRI patterns was described on the basis of prior publications (see reference Cohen-Aubart et al. [7])