A survey exploring caregiver burden and health-related quality of life in hereditary transthyretin amyloidosis

Table 1 Caregiver sample characteristics and proxy-reported patient characteristics

Sample characteristic	Caregivers^a (N = 36)	General population^b (N = 36)
	Mean (SD)	Mean (SD)
Age	56.3 (12.5) ^a	57.5 (13.4) ^b

	N (%)	N (%)
Gender: female	29 (81%) ^a	29 (81%) ^b
Living situation: with partner/spouse	34 (94%)	36 (100%) ^b
Living situation: with relative	2 (5%) ^a	0 (0%)
Employment status: employed full-time	5 (14%)	5 (14%)
Employment status: employed part-time	10 (28%)	10 (28%)
Employment status: homemaker/retired/unemployed/other	20 (56%)	20 (56%)
Employment status: unable to work due to own health	1 (3%) ^a	1 (3%) ^b

Patient characteristic	Mean (SD)
Time since diagnosis (years)	5.76 (4.80) ^a
Age	59.00 (13.38) ^a

	N (%)
Gender: male	28 (78%) ^a
Employment status: employed, full- or part-time	6 (17%)
Ambulatory status*: requires no assistance walking	12 (33%)
Ambulatory status*: requires assistance with walking	21 (58%)
Ambulatory status*: requires wheelchair	2 (6%)
Ambulatory status*: bedridden	1 (3%) ^a
Type of ATTRv: cardiomyopathy	2 (6%)
Type of ATTRv: polyneuropathy	11 (31%)
Type of ATTRv: cardiomyopathy and polyneuropathy	20 (56%) ^a
Type of ATTRv: other/not sure	3 (8%)
V-30 M status: V-30 M variant confirmed	8 (22%)
Symptoms: neuropathic symptom(s) reported	36 (100%) ^a
Symptoms: cardiac symptom(s) reported	26 (72%) ^a
Symptoms: gastrointestinal symptom(s) reported	30 (83%) ^a

^aCharacteristics of the patient-caregiver aged 38 (n=1) and the patient aged 46 who the patient-caregiver was caring for
^bCharacteristics of the matched control aged 38 (n=1)
*Requires no assistance walking, requires assistance with walking and requires wheelchair correspond to Coutinho stages 1, 2 and 3 respectively

ISSN: 1750-1172