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Table 2 Clinical outcomes of all CAEBV patients post HSCT.

From: Post-transplant cyclophosphamide for GVHD prophylaxis in pediatrics with chronic active Epstein-Barr virus infection after haplo-HSCT

Patient

aGVHD location#

cGVHD location$

Early complications

Early infections

Viral reactivation

Survival

Cause of death

PTCy-1

None

None

HC, RPLC

Sepsis, urinary system infection (bacteria)

CMV

Dead

Diffuse alveolar hemorrhage

PTCy-2

Intestine (II)

None

Immunologic lung injury

CMV retinitis

CMV

Alive

–

PTCy-3

None

Digestive tract (M)

None

None

EBV

Alive

–

PTCy-4

None

None

None

None

CMV

Alive

–

PTCy-6

None

None

None

None

None

Alive

–

PTCy-7

None

None

ES, PGF

CMV retinitis

CMV

Alive

–

PTCy-8

None

Lung (M)

Drug-induced seizure

None

CMV, EBV

Alive

–

PTCy-9

None

None

None

None

CMV

Alive

–

  1. #Only grade II-IV aGVHD were listed
  2. $Only moderate (M) and severe (S) cGVHD were shown
  3. aGVHD/cGVHD: acute/chronic GVHD; HC: hemorrhagic cystitis; RPLS: reversible posterior leukoencephalopathy syndrome; PGF: poor graft function; ES: engraftment syndrome. CMV: cytomegalovirus; EBV: Epstein-Bar virus