Table 3 Clinical characteristics of study subjects, colonoscopy findings, polyp burden and follow up (colectomy at 2 years)
From: Microbiome insights into pediatric familial adenomatous polyposis
Subject | Subject | Study year | Polyp burden | Outcome | ||||
|---|---|---|---|---|---|---|---|---|
Gender | Age | APC mutation | Number | Size distribution/mm | Distribution | Colectomy (age) | ||
1 | F | 19 | POSITIVE | 1 | 6–10 | < 5 | A,D | N |
2 | F | 16 | UNKNOWN | 1 | 11–15 | < 5 | PC | N |
3 | F | 17 | 4720delA | 1 | < 5 | < 5 | A,S,R | N |
4 | F | 17 | POSITIVE | 1 | < 5 | 5–10 | D,R | N |
|  |  | 19 |  | 3 | 21–30 | < 5 | C,A,D,S,R |  |
5 | M | 10 | 3183del5 | 1 | 6–10 | < 5 | D,S,R | N |
|  |  | 11 |  | 2 | 5–10 | < 5 | C,A,D,S,R |  |
|  |  | 12 |  | 3 | < 5 | < 5 | C,A,D,S |  |
6 | M | 9 | PV in promoter 1B region | 1 | 6–10 | < 5 | D,S,R | N |
7 | F | 12 | 453delA | 1 | 6–10 | < 5 | T,D,S | N |
8 | M | 6 | Large deletion in the APC gene | 1 | 16–20 | < 5 | PC | N |
| Â | Â | 7 | Â | 2 | Â | Â | Â | Â |
9 | M | 15 | POSITIVE | 2 | 31–50 | < 5 | PC | N |
|  |  | 16 |  | 3 | 31–50 | < 5 | A,T,D,S,R |  |
10 | M | 14 | UNKNOWN | 1 | 6–10 | < 5 | A,D,S,R | N |
|  |  | 15 |  | 2 | 16–20 | < 5 | S,R |  |
11 | F | 12 | NEGATIVE | 1 | Â | Â | Â | Y(13) |
12 | M | 15 | NEGATIVE | 1 | > 50 | 5–10 | PC | Y(15) |
13 | M | 12 | NEGATIVE | 1 | 11–15 | < 5 | PC | Y(14) |