Fig. 1
From: Clinical management guidelines for Friedreich ataxia: best practice in rare diseases
Flow chart of the stages of the guidelines development and stakeholder involvement. Red arrows indicate process for obtaining indirect evidence. CMG = Clinical Management Guidelines; PICO = Patient, Intervention, Comparator, Outcome; FACOMS = Friedreich’s Ataxia Clinical Outcomes Measures; EFACTS = European Friedreich’s Ataxia Consortium for Translational Studies; FRDA = Friedreich ataxia