A common variant in the hepatobiliary phospholipid transporter ABCB4 modulates liver injury in PBC but not in PSC: prospective analysis in 867 patients

Table 4 Risk factors for developing liver cirrhosis in patients with PBC (A) Szczecin, (B) Warsaw

Factor	Univariate analysis	P	Multivariate analysis	P
Factor	Odds ratio	P	Odds ratio	P
(A)
ABCB4 c.711A > T	1.844	0.028	1.769	0.038
Gender	3.325	0.011	3.202	0.015
Age (years)	1.015	0.256
BMI (kg/m²)	0.971	0.832
(B)
ABCB4 c.711A > T	1.649	0.040	1.723	0.033
Gender	3.630	0.017	5.041	0.007
Age (years)	1.056	< 0.001	1.057	< 0.001
BMI (kg/m²)	1.022	0.503

Analyses were performed using uni- and multivariate regression. Abbreviations: please see legend Table 1 and Table 2

ISSN: 1750-1172