Table 2 Auxological parametersf or group 2 (burosumab and rhGH) at moments of interest
From: Growth pattern in children with X-linked hypophosphatemia treated with burosumab and growth hormone
Parameter (SDS) | Pre-pubertal (N = 4) | Pubertal (N = 9) | All (N = 13) | |||
|---|---|---|---|---|---|---|
Mean ± SD | Min/Max | Mean ± SD | Min/Max | Mean ± SD | Min/Max | |
Height at GH0 | − 2.1 ± 0.5 | − 2.8/− 1.6 | − 2.1 ± 0.6 | − 3.3/− 1.2 | − 2.1 ± 0.5 | − 3.3/− 1.2 |
Height at GH1 | − 1.4 ± 0.4 | − 2.0/− 0.8 | − 1.6 ± 0.8 | − 3.1/− 0.5 | − 1.5 ± 0.7 | − 3.1/− 0.5 |
Height at B0 | − 1.0 ± 0.4 | − 1.6/− 0.6 | − 1.3 ± 0.9 | − 3.0/0.0 | − 1.2 ± 0.8 | − 3.0/0.0 |
Height at B1 | − 0.7 ± 0.4 | − 1.2/− 0.1 | − 1.1 ± 0.8 | − 2.5/0.2 | − 0.9 ± 0.7 | − 2.5/0.2 |
BMI at GH0 | 0.5 ± 0.8 | − 0.5/1.6 | 0.1 ± 0.9 | − 1.0/2.1 | 0.2 ± 0.9 | − 1.0/2.1 |
BMI at GH1 | 0.6 ± 0.9 | − 0.4/1.5 | 0.2 ± 0.9 | − 0.8/2.0 | 0.3 ± 0.9 | − 0.8/2.0 |
BMI at B0 | 0.7 ± 0.6 | − 0.1/1.5 | 0.0 ± 0.7 | − 1.0/1.0 | 0.2 ± 0.7 | − 1.0/1.5 |
BMI at B1 | 0.7 ± 0.8 | − 0.1/1.6 | 0.1 ± 0.6 | − 0.7/1.0 | 0.3 ± 0.7 | − 0.7/1.6 |
∆H GH1–GH0 | 0.7 ± 0.1 | 0.5/0.9 | 0.5 ± 0.3 | 0.2/1.2 | 0.6 ± 0.3 | 0.2/1.2 |
∆H B1–B0 | 0.3 ± 0.1 | 0.2/0.5 | 0.2 ± 0.2 | − 0.2/0.5 | 0.2 ± 0.1 | − 0.2/0.5 |
∆H B0–GH0 | 1.1 ± 0.1 | 1.0/1.2 | 1.0 ± 0.5 | 0.3/1.8 | 1.0 ± 0.4 | 0.3/1.8 |
∆BMI B0–GH0 | 0.1 ± 0.2 | − 0.1/0.4 | 0.0 ± 0.4 | − 1.1/0.5 | 0.0 ± 0.4 | − 1.1/0.5 |
∆BMI B1–B0 | 0.0 ± 0.4 | − 0.3/0.7 | 0.1 ± 0.2 | − 0.4/0.4 | 0.0 ± 0.3 | − 0.4/0.7 |