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Table 7 Status of application of drug price calculation adjustment factors in the cost accounting method (old)

From: The actual status of drug prices and adjustment factors for drug price calculation: an analysis of ultra-orphan drug development in Japan

 

Ultra-orphan drugs

Orphan drugs

Non-orphan drugs

n = 18

n = 20

n = 49

Operating profit markup

60%

0

1

0

50%

0

0

1

40%

0

1

1

35%

0

1

0

30%

2

0

1

25%

0

1

0

20%

2

3

5

10%

1

2

9

0%

13

11

31

−5%

0

0

1

Foreign average price adjustment

100% raise

0

0

0

90–99% raise

0

0

1

80–89% raise

0

0

0

70–79% raise

0

0

0

60–69% raise

0

1

0

50–59% raise

0

0

1

40–49% raise

0

0

0

30–39% raise

0

1

0

20–29% raise

0

0

0

10–19% raise

0

1

0

1–9% raise

0

0

1

Not applicable

15

17

41

1–9% lowering

1

0

0

10–19% lowering

1

0

1

20–29% lowering

0

0

0

30–39% lowering

0

0

3

40–49% lowering

0

0

0

50–59% lowering

1

0

0

60–69% lowering

0

0

1

70% and more lowering

0

0

0