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Table 6 Status of application of drug price calculation adjustment factors in the cost accounting method (new)

From: The actual status of drug prices and adjustment factors for drug price calculation: an analysis of ultra-orphan drug development in Japan

 

Ultra-orphan drugs

Orphan drugs

Non-orphan drugs

n = 6

n = 7

n = 14

Premium for usefulness-based group

100%

0

0

0

75%

0

2

0

50%

0

0

0

45%

1

0

1

40%

0

0

1

35%

0

1

1

20%

0

0

1

15%

0

0

0

10%

1

2

0

5%

3

2

1

0%

1

0

9

Premium for marketability-based group

10%

6

7

0

5%

0

0

2

0%

0

0

12

Premium for Sakigake designation scheme

10%

1

0

1

0%

5

7

13

Foreign average price adjustment

100% raise

0

0

0

90–99% raise

0

0

0

80–89% raise

0

0

0

70–79% raise

0

0

0

60–69% raise

0

0

0

50–59% raise

0

0

0

40–49% raise

0

0

0

30–39% raise

0

0

0

20–29% raise

1

0

0

10–19% raise

0

0

0

1–9% raise

0

0

1

Not applicable

5

7

13

1–9% lowering

0

0

0

10–19% lowering

0

0

0

20–29% lowering

0

0

0

30–39% lowering

0

0

0

40–49% lowering

0

0

0

50–59% lowering

0

0

0

60–69% lowering

0

0

0

70% and more lowering

0

0

0