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Table 3 The differences in the expected sales by the expected number of patients

From: The actual status of drug prices and adjustment factors for drug price calculation: an analysis of ultra-orphan drug development in Japan

Expected number of patients

Conjunctive letter of the expected sales

0–9

A

    

10–99

A

    

100–999

 

B

   

1000–9999

  

C

  

10,000–99,999

  

C

D

 

100,000–999,999

    

E

1,000,000 or more

   

D

E

  1. There is a significant difference between groups that are not connected by the same letter. For example, the 0–9 group is not significantly different from the 10–99. On the other hand, there is a significant difference between the 100–999 group and any other groups. Therefore, the 0–9 group is connected to the 10–99 group by A, but the 100–999 group is not connected to any other groups by B