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Fig. 1 | Orphanet Journal of Rare Diseases

Fig. 1

From: Recapitulation of pro-inflammatory signature of monocytes with ACVR1A mutation using FOP patient-derived iPSCs

Fig. 1

Establishment of immortalized monocytic lineage cell lines from FOP- and resFOP-iPSCs. A, Morphology of colonies during monocyte induction from iPSCs. Representative phase contrast images during the step-wise induction stages shown above. Scale bars = 500 μm. B, Representative phase contrast images of monocytes induced from each iPSC line. Scale bars = 500 μm. C, Representative phase contrast images of each ML. Scale bars = 100 μm. D, Representative morphology of each ML stained by May-Giemsa staining. Scale bars = 10 μm. E–F, Flow cytometric analyses of resFOP-ML and FOP-ML for the expression of CD14 (E) and CD16 (F)

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Orphanet Journal of Rare Diseases

ISSN: 1750-1172