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Table 4 Views of different participants on genetic screening

From: Current attitudes and preconceptions on newborn genetic screening in the Chinese reproductive-aged population

  Is it necessary to undergo genetic screening? Value P
Total (n = 1141, 100%) Yes (n = 989, 86.68%) No/I don’t know (n = 152, 13.32%)
Gender
 Male 271 (23.75%) 235 (23.76%) 36 (23.68%) 0.00 P > 0.05
 Female 870 (76.25%) 754 (76.24%) 116 (76.32%)   
Age (years old)
  ≤ 24 41 (3.59%) 37 (3.74%) 4 (2.63%)   
 25–29 443 (38.83%) 380 (38.42%) 63 (41.45%) 5.995 P > 0.05
 30–34 490 (42.94%) 418 (42.27%) 72 (47.37%)   
  ≥ 35 167 (14.64%) 154 (15.57%) 13 (8.55%)   
Have you had family history of genetic disease?
 Yes 3 (0.26%) 3 (0.30%) 0 (0.00%) 0.462 P > 0.05
 No 1138 (99.74%) 986 (99.70%) 152 (100%)   
Nation
 Han nationality 1117 (97.90%) 969 (97.98%) 148 (97.37%) 0.238 P > 0.05
 Others 24 (2.10%) 20 (2.02%) 4 (2.63%)   
Had any abnormalities in your/your spouse's fetus during pregnancy?
 Yes 34 (2.98%) 32 (3.24%) 2 (1.32%) 1.680 P > 0.05
 No 1107 (97.02%) 957 (96.76%) 150 (98.68%)   
If your child is diagnosed with an inherited genetic disease but not treated, will you worry about the aggravation of your child's condition?
 Yes 1120 (98.16%) 977 (98.79%) 143 (94.08%) 16.162 P < 0.05
 No 21 (1.84%) 12 (1.21%) 9 (5.92%)   
Educational background
 Below high school 53 (4.64%) 38 (3.84%) 15 (9.87%) 23.727 P < 0.05
 High school and technical secondary school 103 (9.03%) 83 (8.39%) 20 (13.16%)   
 Junior college/Vocational College 242 (21.21%) 200 (20.22%) 42 (27.63%)   
 Undergraduate or above 743 (65.12%) 668 (67.55%) 75 (49.34%)   
Family income
  < 100 thousand RMB 187 (16.39%) 137 (13.85%) 50 (32.89%)   
 100–250 thousand RMB 577 (50.57%) 508 (51.37%) 69 (45.39%) 40.277 P < 0.05
 260–400 thousand RMB 255 (22.35%) 227 (22.95%) 28 (18.42%)   
  > 400 thousand RMB 122 (10.69%) 117 (11.83%) 5 (3.30%)   
If your child is diagnosed with an inherited genetic disease and requires long-term (lifelong) treatment, how do you think it will affect your family life status?
 Decrease the quality of life, increase daily burden and anxiety, and life becomes negative 267 (23.40%) 227 (22.95%) 40 (26.32%) 0.831 P > 0.05
 Grateful for early detection and treatment for the disease which improves the child’s quality of life 874 (76.60%) 762 (77.05%) 112 (73.68%)