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Table 4 Views of different participants on genetic screening

From: Current attitudes and preconceptions on newborn genetic screening in the Chinese reproductive-aged population

 

Is it necessary to undergo genetic screening?

Value

P

Total (n = 1141, 100%)

Yes (n = 989, 86.68%)

No/I don’t know (n = 152, 13.32%)

Gender

 Male

271 (23.75%)

235 (23.76%)

36 (23.68%)

0.00

P > 0.05

 Female

870 (76.25%)

754 (76.24%)

116 (76.32%)

  

Age (years old)

  ≤ 24

41 (3.59%)

37 (3.74%)

4 (2.63%)

  

 25–29

443 (38.83%)

380 (38.42%)

63 (41.45%)

5.995

P > 0.05

 30–34

490 (42.94%)

418 (42.27%)

72 (47.37%)

  

  ≥ 35

167 (14.64%)

154 (15.57%)

13 (8.55%)

  

Have you had family history of genetic disease?

 Yes

3 (0.26%)

3 (0.30%)

0 (0.00%)

0.462

P > 0.05

 No

1138 (99.74%)

986 (99.70%)

152 (100%)

  

Nation

 Han nationality

1117 (97.90%)

969 (97.98%)

148 (97.37%)

0.238

P > 0.05

 Others

24 (2.10%)

20 (2.02%)

4 (2.63%)

  

Had any abnormalities in your/your spouse's fetus during pregnancy?

 Yes

34 (2.98%)

32 (3.24%)

2 (1.32%)

1.680

P > 0.05

 No

1107 (97.02%)

957 (96.76%)

150 (98.68%)

  

If your child is diagnosed with an inherited genetic disease but not treated, will you worry about the aggravation of your child's condition?

 Yes

1120 (98.16%)

977 (98.79%)

143 (94.08%)

16.162

P < 0.05

 No

21 (1.84%)

12 (1.21%)

9 (5.92%)

  

Educational background

 Below high school

53 (4.64%)

38 (3.84%)

15 (9.87%)

23.727

P < 0.05

 High school and technical secondary school

103 (9.03%)

83 (8.39%)

20 (13.16%)

  

 Junior college/Vocational College

242 (21.21%)

200 (20.22%)

42 (27.63%)

  

 Undergraduate or above

743 (65.12%)

668 (67.55%)

75 (49.34%)

  

Family income

  < 100 thousand RMB

187 (16.39%)

137 (13.85%)

50 (32.89%)

  

 100–250 thousand RMB

577 (50.57%)

508 (51.37%)

69 (45.39%)

40.277

P < 0.05

 260–400 thousand RMB

255 (22.35%)

227 (22.95%)

28 (18.42%)

  

  > 400 thousand RMB

122 (10.69%)

117 (11.83%)

5 (3.30%)

  

If your child is diagnosed with an inherited genetic disease and requires long-term (lifelong) treatment, how do you think it will affect your family life status?

 Decrease the quality of life, increase daily burden and anxiety, and life becomes negative

267 (23.40%)

227 (22.95%)

40 (26.32%)

0.831

P > 0.05

 Grateful for early detection and treatment for the disease which improves the child’s quality of life

874 (76.60%)

762 (77.05%)

112 (73.68%)