Table 3 Participants’ expectation on undergoing genetic screening
Is it necessary to undergo genetic screening? | Value | P | |||
|---|---|---|---|---|---|
Total (n = 1141, 100%) | Yes (n = 989, 86.68%) | No/I don’t know (n = 152, 13.32%) | |||
Do you think it is necessary to increase the number of diseases in NBS? | |||||
Yes | 930 (81.51%) | 861 (87.06%) | 69 (45.39%) | ||
No | 15 (1.31%) | 11 (1.11%) | 4 (2.63%) | 154.865 | P < 0.05 |
Have no idea | 34 (2.98%) | 22 (2.22%) | 12 (7.90%) | ||
Consult doctor | 162 (14.20%) | 95 (9.61%) | 67 (44.08%) | ||
How many new diseases do you wish to be added to NBS? | |||||
As many and comprehensive as possible | 821 (71.96%) | 734 (74.22%) | 87 (57.24%) | 88.685 | P < 0.05 |
Add another 10–50 types with a relatively high incidence | 257 (22.52%) | 225 (22.75%) | 32 (21.05%) | ||
No need to add any new diseases | 63 (5.52%) | 30 (3.03%) | 33 (21.71%) | ||
The cost of NBS may increase with the number of screening diseases. How much are you willing to pay for the NBS after expanding the types of diseases? | |||||
< 1000 RMB | 181 (15.86%) | 135 (13.65%) | 46 (30.26%) | ||
1000–2000 RMB | 678 (59.42%) | 594 (60.06%) | 84 (55.26%) | 30.875 | P < 0.05 |
> 2000 RMB | 282 (24.72%) | 260 (26.29%) | 22 (14.48%) | ||
What is the minimum detection rate for each disease in newborn genetic screening that you can accept? | |||||
> 95% | 625 (54.78%) | 554 (56.02%) | 71 (46.71%) | ||
> 75% | 163 (14.28%) | 148 (14.96%) | 15 (9.87%) | ||
> 60% | 102 (8.94%%) | 87 (8.80%) | 15 (9.87%) | 15.290 | P < 0.05 |
> 30% | 251 (22.00%) | 200 (20.22%) | 51 (33.55%) | ||
For low onset genetic diseases, the detection rate of genetic screening is low. What is the minimum detection rate for these diseases in newborn genetic screening that you can accept? | |||||
> 80% | 586 (51.36%) | 519 (52.48%) | 67 (44.08%) | ||
> 65% | 194 (17.00%) | 164 (16.58%) | 30 (19.74%) | 8.576 | P < 0.05 |
> 50% | 123 (10.78%) | 111 (11.22%) | 12 (7.89%) | ||
> 30% | 238 (20.86%) | 195 (19.72%) | 43 (28.29%) | ||