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Table 2 Quality of life in ENVISION trial participants at baseline

From: Disease burden in patients with acute hepatic porphyria: experience from the phase 3 ENVISION study

Assessment, Mean (SD)

Placebo (n = 46)

Givosiran (n = 48)

SF-12 PCS

38.1 (9.8)

39.5 (9.8)

SF-12 MCS

41.8 (10.3)

39.9 (8.3)

EQ VAS

64.3 (19.6)

62.6 (22.6)

Employed in past 4 weeks, n

21

20

   Days of work missed in past 4 weeks

6.1 (6.5)

3.3 (3.5)

Hours of caregiver support in past week

11.3 (28.1)

12.5 (32.3)

  1. EQ VAS EuroQol visual analog scale, MCS mental component summary, PCS physical component summary, SF-12 12-Item Short-Form Health Survey, version 2