Fig. 3
From: Neuropsychology and MRI correlates of neurodegeneration in SPG11 hereditary spastic paraplegia
Brain volumetry in SPG11 compared to 1:1 age- and gender-matched in-house controls (n = 13, demographic characteristics shown in Additional file 1: Table S1) for different cortical and subcortical regions: (A) cortical regions, (B) white matter regions, (C) corpus callosum, (D) subcortical grey matter regions, (E) infratentorial regions. Bars represent means ± SD of absolute volume values in controls (white) and SPG11 patients (black). Means were compared by unpaired Mann–Whitney test. *p < .05; **p < .01; ***p < .001; ****p < .0001; n.s. not significant