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Fig. 4 | Orphanet Journal of Rare Diseases

Fig. 4

From: Early embryonic lethality in complex I associated p.L104P Nubpl mutant mice

Fig. 4

Nubpl immunofluorescence in Nubpl L104P+/- mice indicated in figure as Nubpl+/− and C57BL/6J brains. A, D, G, J Panoramic hemi-brain; Nubpl expression in magenta and nuclear counterstain (Hoechst) in blue. Approximate coordinate -3 anteroposterior (AP) related to Bregma; AC Mesencephalic coronal section of a NubplL104P+/- male; GI Striatal section of Nubpl +/- male; D-F. Mesencephalic coronal section; JL Striatal coronal section of a 10 months old C57BL/6J control male; C, F magnification of the third ventricle; B, E Zoom into the interpeduncular nucleus of the mesencephalon; H K Magnification in the caudoputamen; I, L Magnification in the cortex. Scale bar for A, G represents 500 µm; B, E, represents 10 µm

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