Table 2 Immunofluorescence, systemic findings, treatment, and outcome of the patients with BSLE
No | Age/Sex | IIF | DIF | ELISA | Systemic findings | SLEDAI | SLE characteristic laboratory values | Treatment | Outcome | ||
|---|---|---|---|---|---|---|---|---|---|---|---|
Anti-BP180 antibody | Anti-BP230 antibody | Anti-type VII collagen antibody | |||||||||
1 | M/36 | Anti-BMZ antibodies located on the dermal side | No data | Negative | Negative | Negative | AIHA, leukopenia, arthritis, LN, NPSLE, serositis | 21 | Hypocomplementemia, ANA H1:320, positive anti-dsDNA and anti-rRNP | GC (pulse), CTX, MMF | Lost |
2 | F/17 | Anti-BMZ antibodies located on the dermal side | Negative | Negative | Negative | Positive | LN | 4 | ANA HS1:80, positive anti-rRNP, anti-Sm and anti-SSA | GC, CsA, HCQ | Lost |
3 | F/13 | Anti-BMZ antibodies located on the dermal side | linear IgG and IgM on BMZ | Negative | Negative | Positive | LN, hemocytopenia | 10 | Hypocomplementemia, ANA H:1280, positive anti-dsDNA and anti-rRNP | GC, CTX, MMF, HCQ | Improved |
4 | M/32 | Negative | Negative | Negative | Negative | Positive | LN, hemocytopenia, PAH, serositis | 25 | Hypocomplementemia, ANA H:1280, positive anti-dsDNA | GC (pulse), CTX | Improved |
5 | F/24 | Anti-BMZ antibodies located on the dermal side | No data | Negative | Negative | Positive | LN, hemocytopenia, myocarditis, NPSLE, serositis | 19 | Hypocomplementemia, ANA S1:80, positive anti-RNP | GC (pulse), HCQ | Lost |
6 | F/13 | Anti-BMZ antibodies located on the dermal side | Linear IgG and IgM on BMZ | Negative | Negative | Positive | LN, hemocytopenia, arthritis, serositis | 3 | Hypocomplementemia, ANA H1:640, positive anti-dsDNA, anti-SSA and anti-SSB | GC (pulse), CTX | Relapsed |
7 | F/36 | Negative | Linear IgG, IgM, IgA and C3 on BMZ | Negative | Negative | Negative | Arthritis, LN, ILD | 6 | ANA S1:1280, positive anti-RNP, anti-SSA and anti-SSB | GC (pulse), CTX, HCQ | Improved |
8 | F/27 | Negative | Negative | Negative | Negative | Positive | LN, IPO, hemocytopenia | 10 | Hypocomplementemia, ANA H1:320, positive anti-dsDNA, anti-SSA and anti-SSB | GC (pulse*2), CTX, FK506, HCQ | Improved |
9 | F/28 | Anti-BMZ antibodies located on the dermal side | No data | Negative | Negative | Negative | LN, hemocytopenia, arthritis, serositis | 20 | Hypocomplementemia, ANA H1:160, positive anti-dsDNA, ACL, and LA | GC (pulse), CTX, HCQ | Improved |
10 | F/22 | Anti-BMZ antibodies located on the dermal side | No data | Negative | Negative | Positive | LN, serositis | 12 | Hypocomplementemia, ANA HS1:320, positive anti-dsDNA, anti-Sm, anti-RNP and anti-SSA | GC, MMF, HCQ | Improved |
11 | F/56 | Negative | Negative | Negative | Negative | Positive | Hemocytopenia, arthritis, | 8 | Hypocomplementemia, ANA S1:160, positive anti-SSA | GC, TGP | Relapsed |
12 | F/7 | Anti-BMZ antibodies located on the dermal side | Linear IgG, IgM, and IgA on BMZ | Negative | Negative | Negative | Hemocytopenia, arthritis, LN, ILD, NPSLE | 18 | Hypocomplementemia, ANA cytoplasmic 1:320, positive anti-dsDNA and anti-rRNP | GC, FK506, HCQ | Improved |