Table 1 Demographic and clinical characteristics of the patients with BSLE
Parameter | Value |
|---|---|
Age at BSLE diagnosis (years, mean ± SD) | 25.9 ± 13.3 |
Sex | |
Female | 10/12 (83.3%) |
Male | 2/12 (16.7%) |
BSLE as an initial feature of SLE | 5/12 (41.7%) |
Distribution of vesiculobullous lesions | |
Head and neck | 10/12 (83.3%) |
Extremities | 9/12 (75.0%) |
Trunk | 7/12 (58.3%) |
Mucosal involvment | 6/12 (50.0%) |
Buccal mucosa | 4/12 (33.3%) |
Lip | 4/12 (33.3%) |
Tongue | 3/12 (25.0%) |
Auricle | 3/12 (25.0%) |
Genital mucosa | 2/12 (16.7%) |
Perianal | 1/12 (8.3%) |
Conjunctiva | 1/12 (8.3%) |
Histological features | |
Subepidermal blister | 8/10 (80.0%) |
Neutrophil infiltrate in blister | 7/10 (70.0%) |
Neutrophil infiltrate in dermis | 7/10 (70.0%) |
Polymorphous infiltrate in dermis | 3/10 (30.0%) |
DIF at the BMZ | 4/8 (50.0%) |
Linear deposition | 4/8 (50.0%) |
IgG deposition | 4/8 (50.0%) |
IgM deposition | 4/8 (50.0%) |
IgA deposition | 2/8 (25.0%) |
C3 deposition | 1/8 (12.5%) |