Table 2 Immunophenotypes and inflammatory markers of FUO patients with chromosomal abnormalities in our cohort
Patient | P1 | P2 | P3 | P4 | P5 | P6 | P7 | P8 | Reference range |
|---|---|---|---|---|---|---|---|---|---|
Age | 52Â m | 67Â m | 21Â m | 48Â m | 60Â m | 51Â m | 22Â m | 12Â m | Â |
Gender | F | F | M | F | F | F | M | M | Â |
WBC (cells/ul) | 23,300↑ | 5700 | 23,210↑ | 23,400 ↑ | 18,000↑ | 15,700↑ | 8300 | 10,700 | 4000–12,000 |
NEUT (%) | 71.4↑ | 55 | 74.4↑ | 55 | 85.4↑ | 57 | 59.2 | 25.8 | 30–70 |
CD19 (%) | 25.35↑ | 15.38 | 24.38 | 18.2 | 9.31↓ | 19.05 | 35.7↑ | 18.82 | 12-24 m: 13.23–26.39; 48-72 m: 10.46–21.77 |
CD19 (cells/ul) | 788.55↑ | 483.06 | 1475.59↑ | 495.95 | 142.81↓ | 678.93 | 1006.77 | 917.87 | 12-24 m: 461–1456; 48-72 m: 303.52–777.25 |
CD3 (%) | 65.62 | 74.35 | 63.69 | 66.63 | 69.94 | 67.36 | 45.38↓ | 61.32 | 12-24 m: 53.88–72.87; 48-72 m: 59.50–75.56 |
CD3 (cells/ul) | 2041.2 | 2335 | 3854.4 | 1815.9 | 1072.6↓ | 2400.8 | 1279.8↓ | 2990 | 12-24 m: 1794–4247; 48-72 m: 1480–2847 |
CD4 (%) | 38.47 | 42.00↑ | 38.26 | 38.69 | 53.14↑ | 17.62↓ | 31.03 | 36.82 | 12-24 m: 24.08–42.52; 48-72 m: 28.49–41.07 |
CD4 (cells/ul) | 1196.79 | 1319.18 | 2315.53↑ | 1054.46 | 814.94 | 628.14↓ | 875.25↓ | 1795.57 | 12-24 m: 902–2253; 48-72 m: 767–1592 |
CD8 (%) | 21.96 | 25.5 | 21.74 | 21.95 | 16.3↓ | 46.56↑ | 10.08↓ | 22.17 | 12-24 m:19.00–32.51; 48-72 m: 19.70–32.04 |
CD8 (cells/ul) | 683.00 | 800.81 | 1315.9 | 598.19 | 249.91↓ | 1659.24↑ | 284.28↓ | 1080.9 | 12-24 m:580–1735; 48-72 m: 553–1127 |
CD16CD56 (%) | 6.74↓ | 8.84 | 11.24 | 13.61 | 18.72 | 12.83 | 16.54 | 18.65 | 12-24 m: 7.21–20.9; 48-72 m: 7.83–20.99 |
CD16CD56 (cells/ul) | 209.56↓ | 277.64 | 680.25 | 370.2 | 287.17 | 457.14 | 466.52 | 909.37 | 12-24 m: 270–1053; 48-72 m: 227–668 |
IgG (g/L) | 7.60 | 13.2 ↑ | 7 | 10.5 | 19.8 ↑ | 6.5 | 7.1 | 10.2↑ | 12-24 m: 5.52–11.46; 48-72 m: 4.95–12.74 |
IgM (g/L) | 1.55 | 2.27 ↑ | 1.01 | 1.81 | 1.96 | 1.59 | 0.7 | 0.37 | 12-24 m: 0.6–2.12; 48-72 m: 0.65–2.01 |
IgA (g/L) | 0.52 | 1.19 | 0.48 | 0.67 | 2.8 ↑ | 0.85 | 0.3 | 0.21 | 12-24 m: 0.06–0.74; 48-72 m: 0.33–1.89 |
IgE (KU/L) | 171.6 ↑ | 32.55 | 34.18 | 31.13 | 3006.67 ↑ | 37.42 | 7.1 | 29.72 |  < 100 |
CRP (mg/L) | 87 ↑ | 16 ↑ | 27.18 ↑ | 70 ↑ | 40 ↑ | 132 ↑ |  < 8 |  < 0.5 |  < 8 |
ESR (mm/h) | 48 ↑ | 32 ↑ | 64 ↑ | 44 ↑ | 54 ↑ | 107 ↑ | 35↑ | 2 | 0–26 |
SAA (mg/L) | NA | 259.6 ↑ | 256.4 ↑ | NA | NA | NA |  < 2.5 |  < 2.5 |  < 10 |
IL-2 (pg/ml) | NA | 1.3* | 0* | NA | 1.71 | NA | 0 | 2.3 | 0–11.4 |
IL-4 (pg/ml) | NA | 1.35* | 0* | NA | 2.32 | NA | 0 | 0.8 | 0–12.9 |
IL-6 (pg/ml) | 109.6 ↑ | 2.86* | 0.8* | 7.6* | 44.79 ↑ | 667.7 ↑ | 0 | 5.9 | 0–16.6 |
IL-8 (pg/ml) | NA | NA | NA | NA | NA | 4956.86 ↑ | NA | NA | 0–21.4 |
IL-10 (pg/ml) | NA | 3.56* | 2.1* | NA | 10.64 ↑ | 12.95 ↑ | 1.07 | 6 | 0–5.9 |
TNF-α (pg/ml) | NA | 2.27* | 0* | NA | 90.96 ↑ | 11.03↑ | 0 | 3.6 | 0–5.5 |
IFN-γ (pg/ml) | NA | 2.64* | 0* | NA | NA | NA | 0 | 1.5 | 0–17.3 |