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Table 1 Self-reported frequency of symptoms pre-ERT, n = 11

From: Burden associated with Fabry disease and its treatment in 12–15 year olds: results from a European survey

Symptom Experienced

Pre-ERT

 

Always

Often

Sometimes

Seldom

Never

Burning in the hands and feet

4 (36%)

4 (36%)

1 (9%)

1 (9%)

1 (9%)

Sweating less than normal

5 (45%)

2 (18%)

1 (9%)

2 (18%)

1 (9%)

Sensitive to heat or cold

5 (45%)

2 (18%)

1 (9%)

2 (18%)

1 (9%)

Pain

3 (27%)

4 (36%)

3 (27%)

0 (0%)

1 (9%)

Stomach pain/bloating after eating

2 (18%)

4 (36%)

3 (27%)

1 (9%)

1 (9%)

Tiredness that is not relieved by rest or sleep

2 (18%)

3 (27%)

1 (9%)

4 (36%)

1 (9%)

Feeling sick/being sick

0 (0%)

3 (27%)

4 (36%)

1 (9%)

3 (27%)

Diarrhoea

0 (0%)

1 (9%)

5 (45%)

3 (27%)

2 (18%)

Dizziness

0 (0%)

2 (18%)

2 (18%)

4 (36%)

3 (27%)

Small dark red/purple spots usually found between your belly button and knees

1 (9%)

2 (18%)

0 (0%)

2 (18%)

6 (55%)

Depression/feeling down

0 (0%)

1 (9%)

4 (36%)

0 (0%)

6 (55%)

Ringing in ears

0 (0%)

1 (9%)

3 (27%)

1 (9%)

6 (55%)

Shortness of breath

0 (0%)

0 (0%)

1 (9%)

5 (45%)

5 (45%)

Irregular heartbeat

0 (0%)

0 (0%)

2 (18%)

3 (27%)

6 (55%)

Weight gain/weight loss

0 (0%)

1 (9%)

1 (9%)

3 (27%)

6 (55%)

Cough/wheezing

0 (0%)

0 (0%)

0 (0%)

6 (55%)

5 (45%)

Problems with eyesight

0 (0%)

0 (0%)

0 (0%)

3 (27%)

8 (73%)

  1. Frequency with which patients reported experiencing each listed symptom as occurring before beginning ERT. Patients recorded each symptom as occurring at a frequency of; always, often, sometimes, seldom or never. Both the number of patients and percentage of patients reporting each symptom frequency is shown. Symptoms are ranked in order of most frequently reported pre-ERT