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Table 3 Site and frequency of spontaneous hemorrhage by severity of hemophilia (n = 44)

From: Clinical profile and demographic characteristics of moderate and severe hemophilia patients in a tertiary care hospital of Bangladesh

Variables

Proportion of Events

p value

Number of Events

p value

Total (n = 44) n (%)

Severe (n = 19) n (%)

Moderate (n = 25) n (%)

Total (n = 44) (min–max)

Severe (n = 19) (min–max)

Moderate (n = 25) (min–max)

Spontaneous bleeding (last 2 years)

    

32 (0–97)

49 (2–95)

27 (0–97)

0.157

Bruises and ecchymosis

18 (40.9)

10 (52.6)

8 (32.0)

0.168

3 (1–12)

1.5 (1–6)

3.5 (2–12)

0.016

Joint hemorrhage

Knee

39 (88.6)

16 (94.2)

23 (92.0)

0.638

12 (1–40)

10 (2–32)

12 (1–40)

0.944

Ankle

30 (68.2)

14 (73.7)

16 (64.0)

0.495

3.5 (1–20)

4 (1–20)

3 (1–20)

0.951

Elbow

30 (68.2)

14 (73.7)

16 (64.0)

0.495

9 (1–32)

11 (2–32)

8.5 (1–24)

0.257

Wrist joint

12 (27.9)

7 (36.8)

5 (20.8)

0.245

3 (1–10)

3 (1–8)

3 (1–10)

0.876

Hip joint

13 (30.2)

7 (36.8)

6 (25.0)

0.401

2 (1–12.0)

1.5 (1–4)

2 (2–12)

0.394

Shoulders

18 (41.9)

6 (31.6)

12 (50.0)

0.224

2 (1–40)

9.5 (1–40)

2 (1–10)

0.125

Muscle hemorrhage

Iliopsoas

12 (27.9)

6 (33.3)

6 (24.0)

0.712

1 (1–10)

1.5 (1–10)

1 (1–4)

0.589

Buttock

9 (20.9)

3 (16.7)

6 (24.0)

0.361

2 (1–6)

2 (2)

1.5 (1–6)

0.714

Calf muscle

16 (37.2)

7 (38.9)

9 (36.0)

0.847

1.5 (1–10)

2 (1–10)

1 (1–10)

0.837

Thigh

22 (50.0)

10 (52.6)

12 (48.0)

0.761

2 (1–12)

2 (1–8)

2 (1–12)

0.923

Flexor muscles of forearm

11 (25.0)

4 (21.1)

7 (28.0)

0.731

2 (1–10)

5 (1–10)

2 (1–6)

0.412

Scalp

1 (2.3)

1 (4.0)

1.000

1

1

Facial

4 (9.1)

2 (10.5)

2 (8.0)

1.000

1 (1–2)

1 (1)

1.5 (1–2)

1.000

Mucosal bleeding

Gum bleeding

22 (50.0)

11 (57.9)

11 (44.0)

0.543

1 (1–10)

4 (1–20)

1 (1–20)

0.243

Epistaxis

6 (13.6)

3 (15.8)

3 (12.0)

1.000

1 (1–10)

1 (1–10)

1 (1–2)

1.000

Gastrointestinal bleeding

Hematemesis

2 (4.5)

1 (5.3)

1 (4.0)

1.000

2 (1–3)

3

1

1.000

Melaena

11 (25.0)

5 (26.3)

6 (24.0)

1.000

2 (1–7)

4 (1–7)

1 (1–2)

0.082

Oro-pharyngeal

6 (13.6)

2 (10.5)

4 (16.0)

0.684

3 (1–4)

2.5 (1–4)

3 (1–4)

1.000

Retroperitoneal

12 (27.3)

5 (26.3)

7 (28.0)

0.901

1 (1–4)

3 (2–4)

1 (1–2)

0.095

Hemoptysis

3 (6.8)

3 (15.8)

0.073

2 (1–4)

2 (1–4)

Ocular bleeding

Subconjunctival hemorrhage

5 (11.4)

3 (15.8)

2 (8.0)

0.638

1 (1–2)

1 (1–2)

1 (1)

0.800

Vitreous hemorrhage

1 (2.3)

1 (4.2)

1.000

Genito-urinary bleeding

16 (36.4)

9 (47.4)

7 (28.0)

0.220

1 (1–5)

1 (1–5)

1 (1–2)

0.470

  1. p value was determined by Fisher’s exact test, Chi-square test and Mann–Whitney U test where appropriate; Significant p value was shown in bold