From: A conceptual disease model for quality of life in mitochondrial disease
 | Outcome measure | Bivariate regression coefficient | Multivariate regression coefficient | |
---|---|---|---|---|
Correlation with QoL general health (SF 36 GH) | Regression coefficient (B (95% CI)) | Standardized coefficient (Beta) | ||
 | Constant |  | 55.32 (13.07 to 97.56) |  |
Biological and physiological | Disease manifestation (NMDAS) |  − 0.34 |  − 0.03 (− 0.69 to 0.09) |  − 0.19 |
Symptom status | Depression (BDI-PC) |  − 0.34 | 0.38 (− 1.46 to 2.22) | 0.06 |
Fatigue (CIS F) |  − 0.59 |  − 0.64 (− 1.02 to − 0.27)** |  − 0.36 | |
Cognitive functioning (MOCA) | 0.09 |  − 0.73 (− 2.08–0.63) |  − 0.13 | |
Functional health | Societal participation (USERP F) | 0.36 | 0.05 (− 0.33–0.42) | 0.03 |
Health perceptions | QoL physical functioning (SF36 PF) | 0.48 | 0.17 (0.01–0.33)* | 0.08 |
QoL mental health (SF36 MH) | 0.34 | 0.20 (− 0.14–0.54) | 0.20 | |
QoL social functioning (SF36 SF) | 0.56 | 0.06 (− 0.14–0.26) | 0.26 |