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Table 4 Hierarchical regression model overall QoL

From: A conceptual disease model for quality of life in mitochondrial disease

 

Outcome measure

Bivariate regression coefficient

Multivariate regression coefficient

Correlation with QoL general health (SF 36 GH)

Regression coefficient (B (95% CI))

Standardized coefficient (Beta)

 

Constant

 

55.32 (13.07 to 97.56)

 

Biological and physiological

Disease manifestation (NMDAS)

 − 0.34

 − 0.03 (− 0.69 to 0.09)

 − 0.19

Symptom status

Depression (BDI-PC)

 − 0.34

0.38 (− 1.46 to 2.22)

0.06

Fatigue (CIS F)

 − 0.59

 − 0.64 (− 1.02 to − 0.27)**

 − 0.36

Cognitive functioning (MOCA)

0.09

 − 0.73 (− 2.08–0.63)

 − 0.13

Functional health

Societal participation (USERP F)

0.36

0.05 (− 0.33–0.42)

0.03

Health perceptions

QoL physical functioning (SF36 PF)

0.48

0.17 (0.01–0.33)*

0.08

QoL mental health (SF36 MH)

0.34

0.20 (− 0.14–0.54)

0.20

QoL social functioning (SF36 SF)

0.56

0.06 (− 0.14–0.26)

0.26

  1. Bold values indicate significance results
  2. *p < 0.05; **p < 0.01