Clinical evaluation of non-invasive prenatal screening for the detection of fetal genome-wide copy number variants

Table 1 Maternal indications of fetal CNV detected by NIPS

Groups	n	Prenatal diagnosis by CMA			PPV (%)
Groups	n	n	TP	FP	PPV (%)
Advanced age women	39	13	4	9	30.8
High risk of prenatal screening	31	12	4	8	33.3
Intermediate risk of prenatal screening	46	20	12	8	60.0
Voluntary demand	71	36	15	21	41.7
Others*	25	15	2	13	13.3
Total	212	96	37	59	38.5

ISSN: 1750-1172