Table 3 Results of ADAMTS13 antigen and anti-ADAMTS13 antibodies in patients with and without severely deficient ADAMTS13 activity
From: Lombardy diagnostic and therapeutic network of thrombotic microangiopathy
ADAMTS13 < 10% (n = 36) | ADAMTS13 ≥ 10% (n = 8) | |
|---|---|---|
ADAMTS13 antigen | ||
Reduced, n (%) | 34 (94) | 3 (38) |
Normal, n (%) | 2 (6) | 5 (62) |
Titer, ug/ml, median (IQR) | 0.1 (0.04–0.16) | 0.66 (0.53–0.72) |
Anti-ADAMTS13 antibodies | ||
Negative or borderline, n (%) | 2 (6) | 6 (75) |
Positive, n (%) | 34 (94) | 2 (25) |
Titer, U/ml, median (IQR) | 63 (39–93) | 18; 21a |