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Table 1 Basic characteristics and quality rating of the included studies

From: The health-related quality of life, mental health and mental illnesses of patients with inclusion body myositis (IBM): results of a mixed methods systematic review

Study, year Context country Study design Study population total/N Female IBM
n/%
Applied diagnostic criteria IBM
n
Risk of bias assessment
NOS AXIS MMAT
Feldon et al. [34], 2017 USA, Canada Cross-sectional IIM 1648/
PM 481
DM 702
IBM 465
186/40 n not stated; possible or probable IBM [40];* 7/9 Yes: 11
No: 5
Do not know: 4
Yes: 5
No: 0
Can’t tell: 0
Goyal et al. [36], 2016 USA Cross-sectional IBM 25 6/24 19 clinically defined IBM, 6 probable IBM [42] 5/9 Yes: 12
No: 3
Do not know: 5
Yes: 2
No: 1
Can’t tell: 2
Rose et al. [39], 2012 USA Cross-sectional NMD 302/
LGMD 91
FSHD 49
PM/DM 19
IBM 24
MD 79
Misc 40
6/25  > 6 months with confirmed diagnosis** 7/9 Yes: 14
No: 2
Do not know: 4
Yes: 4
No: 0
Can’t tell: 1
Sadjadi et al. [38], 2010 UK Cross-sectional (RCT data) IBM 60 22/37 n not stated; definite or possible IBM [40] 6/9 Yes: 8
No: 4
Do not know: 8
Yes: 4
No: 0
Can’t tell: 1
Gibson et al. [35], 2016 USA Qualitative IBM 10 4/40 10 clinicopathologically defined IBM [42] Yes: 5
No: 0
Can’t tell: 0
Ortega et al. [37], 2010 Australia Qualitative IIM 14/
PM 8
DM 4
IBM 2
not stated n not stated; applied criteria [41] “South Australian Database for Patients With Biopsy-Proven Inflammatory Myositis” Yes: 1
No: 1
Can’t tell: 3
  1. AXIS: Appraisal tool for Cross-Sectional Studies; DM: dermatomyositis; FSHD: facioscapulohumeral muscular dystrophy; IBM: inclusion body myositis; IIM: idiopathic inflammatory myopathies; IQR: interquartile range; LGMD: limb girdle muscular dystrophies; MD: myotonic dystrophy; MMAT: Mixed Methods Appraisal Tool; NMD: neuromuscular diseases; NOS: Newcastle–Ottawa scale; PM: polymyositis
  2. *Additional validation of patients’ self-reports with a partial sample (6.7% of N), 87% matching with a physician’s diagnose
  3. **Muscle biopsy, genetics, raised creatine kinase levels, neurophysiology, expert opinion