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Table 3 Generic and condition-specific health-related quality of life in symptom subgroups of children with delayed reconstruction of esophageal atresia

From: Postoperative morbidity and health-related quality of life in children with delayed reconstruction of esophageal atresia: a nationwide Swedish study

   Physical functioning Emotional functioning Social functioning
Symptoms the past four weeks   n, yes Median(range) n, no Median(range) p-value n, yes Median(range) n, no Median(range) p-value n, yes Median(range) n, no Median(range) p-value
Generic health-related quality of life
Child-Report Swallowing difficulties 5 59.4 (40.6–100) 15 93.8 (65.6–100) 0.21 5 70.0 (60.0–100) 15 90.0 (65.0–100) 0.37 5 70.0 (50.0–100) 15 100 (50.0–100) 0.16
Heartburn 5 87.5 (40.6–93.8) 15 100 (56.3–100) 0.054 5 85.0 (65.0–100) 15 95.0 (60.0–100) 0.35 5 95.0 (50.0–100) 15 100 (50.0–100) 0.26
Cough 7 87.5 (40.6–100) 13 100 (65.6–100) 0.046 7 85.0(60.0–100) 13 95.0 (65.0–100) 0.29 7 95.0 (50.0–100) 13 100(50.0–100) 0.21
Airway infections 5 84.4 (40.6–93.8) 15 100 (59.4–100) 0.025 5 70.0 (60.0–100) 15 95.0 (65.0–100) 0.075 5 70.0 (50.0–100) 15 100 (55.0–100) 0.020
Parent-report Swallowing difficulties 5 56.3 (56.3–100) 17 98.4 (31.3–100) 0.091 5 80.0 (55.0–100) 17 95.0 (30.0–100) 0.35 5 67.5 (60.0–100) 17 95.0 (20.0–100) 0.36
Heartburn 6 57.8 (31.3–87.5) 16 100 (56.3–100) 0.003 6 70.0 (30.0–100) 16 95.0 (55.0–100) 0.041 6 67.5 (20.0–100) 15 95.0 (60.0–100) 0.084
Cough 8 57.8 (31.3–87.5) 13 100 (65.6–100)  < 0,001 9 80.0 (30.0–100) 13 95.0 (70.0–100) 0.026 8 67.5 (20.0100) 13 100 (70.0–100) 0.036
Airway infections 6 57.8 (31.2–100) 15 100 (56.3–100) 0.017 6 57.5 (30.0–100) 16 95.0 (70.0–100) 0.096 6 60.0 (20.0–100) 15 95.0 (70.0–100) 0.009
   School functioning Total PedsQL 4.0 scores
Symptoms the past four weeks   n, yes Median(range) n, no Median(range) p-value n, yes Median(range) n, no Median(range) p-value
Generic health-related quality of life
Child-Report Swallowing difficulties 5 60.0 (55.0–100) 11 90.0 (40.0–100) 0.40 5 60.9 (52.2–100) 15 87.0 (63.0–100) 0.19
Heartburn 5 60.0 (55.0–65.0) 15 90.0 (40.0–100) 0.027 5 84.8 (52.2–87.0) 15 94.6 (61.0–100) 0.044
Cough 7 60.0 (55.0–100) 13 94.6 (63.0–100) 0.077 7 84.8 (52.2–100) 13 93.5 (78.3–100) 0.080
Airway infections 5 55.0 (40.0–65.0) 15 90.0 (40.0–100) 0.006 5 63.0 (52.2–87.0) 15 94.6 (60.0–100) 0.014
Parent-report Swallowing difficulties 5 60.0 (55.0–100) 17 55.0 (15.0–100) 0.61 5 69.6 (56.5–100) 17 85.9 (27.2–100) 0.19
Heartburn 6 55.0 (15.0–75.0) 16 87.5 (35.0–100) 0.009 6 64.1 (27.2–85.9) 16 91.8 (56.5–100) 0.009
Cough 9 60.0 15.0–100) 13 90.0 (35.0–100) 0.017 9 69.6 (27.2–100) 13 93.5 (78.3–100) 0.007
Airway infections 6 45.0 (15.0–60.0) 16 87.5 (50.0–100) 0.001 6 57.6 (27.2–85.9) 16 91.8 (69.6–100) 0.004
   Eating Social relationships Body perception
Symptoms the past four weeks   n, yes Median(range) n, no Median(range) p-value n, yes Median(range) n, no Median(range) p-value n, yes Median(range) n, no Median(range) p-value
Condition-specific health-related quality of life
Child report Swallowing difficulties 5 43.8 (17.9–59.4) 14 81.3 (53.1–100) 0.002 5 66.1 (57.1–85.7) 14 91.1 (42.9–100) 0.048 5 90.0 (75.0–95.0) 14 95.0 (80.0–100) 0.13
Heartburn 5 75.0 (17.9–84.4) 15 78.1 (43.8–100) 0.29 5 73.2 (57.1–89.3) 15 89.3 (32.1–100) 0.27 5 85.0 (75.0–100) 15 95.0 (60.0–100) 0.30
Cough 7 59.4 (17.9–84.4) 13 81.3 (43.8–100) 0.080 6 73.2 (57.1–89.3) 13 92.8 (32.1–100) 0.13 7 95.0 (75.0–100) 13 90.0 (60.0–100) 0.54
Airway infections 5 59.4 (17.9–84.4) 15 78.1 (40.6–100) 0.26 5 66.1 (42.9–89.3) 15 89.3 (32.1–100) 0.11 5 95.0 (80.0–100) 15 90.0 (60.0–100) 0.86
Parent-report Swallowing difficulties 5 50.0 (30.0–60.3) 16 87.5 (50.0–100) 0.002 5 74.1 (53.6–89.3) 16 96.4 (42.9–100) 0.15 5 80.0 (50.0–95.0) 16 90.0 (65.0–100) 0.51
Heartburn 6 51.6 (30.0–96.9) 16 84.4 (50.0–100) 0.024 5 62.2 (42.9–71.4) 16 94.6 (46.4–100) 0.020 5 65.0 (50.0–80.0) 16 92.5 (55.0–100) 0.006
Cough 9 53.1 (30.0–96.9) 13 90.6 (50.0–100) 0.004 9 71.4 (42.9–89.3) 13 100 (46.4–100) 0.039 9 72.5 (50.0–95.0) 13 90.0 (55.0–100) 0.030
Airway infections 6 56.3 (30.0–96.9) 16 84.4 (40.6–100) 0.10 5 71.1 (46.4–89.3) 16 94.6 (42.9–100) 0.12 5 75.0 (65.0–95.0) 16 90.0 (50.0–100) 0.19
   Health & well-being Total EA-QOL
Symptoms the past four weeks   n, yes Median(range) n, no Median(range) p-value n, yes Median(range) n, no Median(range) p-value
Condition-specific health-related quality of life
Child report Swallowing difficulties 5 50.0 (43.8–87.5) 14 90.6 (68.8–100) 0.031 5 64.6 (45.3–78.1) 14 88.5 (62.5–100) 0.0046
Heartburn 5 68.8 (50.0–93.8) 15 87,5 (43.8–100) 0.13 5 79.2 (45.3–90.6) 15 85.4 (61.5–100) 0.15
Cough 7 68.8 (43.8–93.8) 13 87.5 (75.0–100) 0.037 7 78.1 (45.3–90.6) 13 86.5 (61.5–100) 0.052
Airway infections 5 69.8 (43.8–93.8) 15 87.5 (50.0–100) 0.046 5 64.6 (45.3–90.6) 15 85.4 (54.2–100) 0.097
Parent-report Swallowing difficulties 5 56.3 (41.7–81.3) 16 87.5 (62.5–100) 0.011 5 64.6 (47.9–74.0) 16 90.6 (55.2–100) 0.013
Heartburn 5 62.5 (41.7–81.3) 16 87.5 (56.3–100) 0.007 5 55.4 (47.9–80.1) 16 90.1 (64.6–100) 0.006
Cough 9 65.6 (41.7–81.3) 13 87.5 (75.0–100) 0.001 9 69.0 (47.9–80.2) 13 92.7 (64.6–100) 0.006
Airway infections 5 62.5 (41.7–87.5) 16 84.4 (50.0–100) 0.072 5 69.8 (55.4–80.2) 16 90.1 (47.9–100) 0.090
  1. Significant level was p < 0.05. Significant p-values are marked with bold text