|  | Physical functioning | Emotional functioning | Social functioning | ||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Symptoms the past four weeks | Â | n, yes | Median(range) | n, no | Median(range) | p-value | n, yes | Median(range) | n, no | Median(range) | p-value | n, yes | Median(range) | n, no | Median(range) | p-value |
Generic health-related quality of life | ||||||||||||||||
Child-Report | Swallowing difficulties | 5 | 59.4 (40.6–100) | 15 | 93.8 (65.6–100) | 0.21 | 5 | 70.0 (60.0–100) | 15 | 90.0 (65.0–100) | 0.37 | 5 | 70.0 (50.0–100) | 15 | 100 (50.0–100) | 0.16 |
Heartburn | 5 | 87.5 (40.6–93.8) | 15 | 100 (56.3–100) | 0.054 | 5 | 85.0 (65.0–100) | 15 | 95.0 (60.0–100) | 0.35 | 5 | 95.0 (50.0–100) | 15 | 100 (50.0–100) | 0.26 | |
Cough | 7 | 87.5 (40.6–100) | 13 | 100 (65.6–100) | 0.046 | 7 | 85.0(60.0–100) | 13 | 95.0 (65.0–100) | 0.29 | 7 | 95.0 (50.0–100) | 13 | 100(50.0–100) | 0.21 | |
Airway infections | 5 | 84.4 (40.6–93.8) | 15 | 100 (59.4–100) | 0.025 | 5 | 70.0 (60.0–100) | 15 | 95.0 (65.0–100) | 0.075 | 5 | 70.0 (50.0–100) | 15 | 100 (55.0–100) | 0.020 | |
Parent-report | Swallowing difficulties | 5 | 56.3 (56.3–100) | 17 | 98.4 (31.3–100) | 0.091 | 5 | 80.0 (55.0–100) | 17 | 95.0 (30.0–100) | 0.35 | 5 | 67.5 (60.0–100) | 17 | 95.0 (20.0–100) | 0.36 |
Heartburn | 6 | 57.8 (31.3–87.5) | 16 | 100 (56.3–100) | 0.003 | 6 | 70.0 (30.0–100) | 16 | 95.0 (55.0–100) | 0.041 | 6 | 67.5 (20.0–100) | 15 | 95.0 (60.0–100) | 0.084 | |
Cough | 8 | 57.8 (31.3–87.5) | 13 | 100 (65.6–100) |  < 0,001 | 9 | 80.0 (30.0–100) | 13 | 95.0 (70.0–100) | 0.026 | 8 | 67.5 (20.0100) | 13 | 100 (70.0–100) | 0.036 | |
Airway infections | 6 | 57.8 (31.2–100) | 15 | 100 (56.3–100) | 0.017 | 6 | 57.5 (30.0–100) | 16 | 95.0 (70.0–100) | 0.096 | 6 | 60.0 (20.0–100) | 15 | 95.0 (70.0–100) | 0.009 |
 |  | School functioning | Total PedsQL 4.0 scores | ||||||||
---|---|---|---|---|---|---|---|---|---|---|---|
Symptoms the past four weeks | Â | n, yes | Median(range) | n, no | Median(range) | p-value | n, yes | Median(range) | n, no | Median(range) | p-value |
Generic health-related quality of life | |||||||||||
Child-Report | Swallowing difficulties | 5 | 60.0 (55.0–100) | 11 | 90.0 (40.0–100) | 0.40 | 5 | 60.9 (52.2–100) | 15 | 87.0 (63.0–100) | 0.19 |
Heartburn | 5 | 60.0 (55.0–65.0) | 15 | 90.0 (40.0–100) | 0.027 | 5 | 84.8 (52.2–87.0) | 15 | 94.6 (61.0–100) | 0.044 | |
Cough | 7 | 60.0 (55.0–100) | 13 | 94.6 (63.0–100) | 0.077 | 7 | 84.8 (52.2–100) | 13 | 93.5 (78.3–100) | 0.080 | |
Airway infections | 5 | 55.0 (40.0–65.0) | 15 | 90.0 (40.0–100) | 0.006 | 5 | 63.0 (52.2–87.0) | 15 | 94.6 (60.0–100) | 0.014 | |
Parent-report | Swallowing difficulties | 5 | 60.0 (55.0–100) | 17 | 55.0 (15.0–100) | 0.61 | 5 | 69.6 (56.5–100) | 17 | 85.9 (27.2–100) | 0.19 |
Heartburn | 6 | 55.0 (15.0–75.0) | 16 | 87.5 (35.0–100) | 0.009 | 6 | 64.1 (27.2–85.9) | 16 | 91.8 (56.5–100) | 0.009 | |
Cough | 9 | 60.0 15.0–100) | 13 | 90.0 (35.0–100) | 0.017 | 9 | 69.6 (27.2–100) | 13 | 93.5 (78.3–100) | 0.007 | |
Airway infections | 6 | 45.0 (15.0–60.0) | 16 | 87.5 (50.0–100) | 0.001 | 6 | 57.6 (27.2–85.9) | 16 | 91.8 (69.6–100) | 0.004 |
 |  | Eating | Social relationships | Body perception | ||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Symptoms the past four weeks | Â | n, yes | Median(range) | n, no | Median(range) | p-value | n, yes | Median(range) | n, no | Median(range) | p-value | n, yes | Median(range) | n, no | Median(range) | p-value |
Condition-specific health-related quality of life | ||||||||||||||||
Child report | Swallowing difficulties | 5 | 43.8 (17.9–59.4) | 14 | 81.3 (53.1–100) | 0.002 | 5 | 66.1 (57.1–85.7) | 14 | 91.1 (42.9–100) | 0.048 | 5 | 90.0 (75.0–95.0) | 14 | 95.0 (80.0–100) | 0.13 |
Heartburn | 5 | 75.0 (17.9–84.4) | 15 | 78.1 (43.8–100) | 0.29 | 5 | 73.2 (57.1–89.3) | 15 | 89.3 (32.1–100) | 0.27 | 5 | 85.0 (75.0–100) | 15 | 95.0 (60.0–100) | 0.30 | |
Cough | 7 | 59.4 (17.9–84.4) | 13 | 81.3 (43.8–100) | 0.080 | 6 | 73.2 (57.1–89.3) | 13 | 92.8 (32.1–100) | 0.13 | 7 | 95.0 (75.0–100) | 13 | 90.0 (60.0–100) | 0.54 | |
Airway infections | 5 | 59.4 (17.9–84.4) | 15 | 78.1 (40.6–100) | 0.26 | 5 | 66.1 (42.9–89.3) | 15 | 89.3 (32.1–100) | 0.11 | 5 | 95.0 (80.0–100) | 15 | 90.0 (60.0–100) | 0.86 | |
Parent-report | Swallowing difficulties | 5 | 50.0 (30.0–60.3) | 16 | 87.5 (50.0–100) | 0.002 | 5 | 74.1 (53.6–89.3) | 16 | 96.4 (42.9–100) | 0.15 | 5 | 80.0 (50.0–95.0) | 16 | 90.0 (65.0–100) | 0.51 |
Heartburn | 6 | 51.6 (30.0–96.9) | 16 | 84.4 (50.0–100) | 0.024 | 5 | 62.2 (42.9–71.4) | 16 | 94.6 (46.4–100) | 0.020 | 5 | 65.0 (50.0–80.0) | 16 | 92.5 (55.0–100) | 0.006 | |
Cough | 9 | 53.1 (30.0–96.9) | 13 | 90.6 (50.0–100) | 0.004 | 9 | 71.4 (42.9–89.3) | 13 | 100 (46.4–100) | 0.039 | 9 | 72.5 (50.0–95.0) | 13 | 90.0 (55.0–100) | 0.030 | |
Airway infections | 6 | 56.3 (30.0–96.9) | 16 | 84.4 (40.6–100) | 0.10 | 5 | 71.1 (46.4–89.3) | 16 | 94.6 (42.9–100) | 0.12 | 5 | 75.0 (65.0–95.0) | 16 | 90.0 (50.0–100) | 0.19 |
 |  | Health & well-being | Total EA-QOL | ||||||||
---|---|---|---|---|---|---|---|---|---|---|---|
Symptoms the past four weeks | Â | n, yes | Median(range) | n, no | Median(range) | p-value | n, yes | Median(range) | n, no | Median(range) | p-value |
Condition-specific health-related quality of life | |||||||||||
Child report | Swallowing difficulties | 5 | 50.0 (43.8–87.5) | 14 | 90.6 (68.8–100) | 0.031 | 5 | 64.6 (45.3–78.1) | 14 | 88.5 (62.5–100) | 0.0046 |
Heartburn | 5 | 68.8 (50.0–93.8) | 15 | 87,5 (43.8–100) | 0.13 | 5 | 79.2 (45.3–90.6) | 15 | 85.4 (61.5–100) | 0.15 | |
Cough | 7 | 68.8 (43.8–93.8) | 13 | 87.5 (75.0–100) | 0.037 | 7 | 78.1 (45.3–90.6) | 13 | 86.5 (61.5–100) | 0.052 | |
Airway infections | 5 | 69.8 (43.8–93.8) | 15 | 87.5 (50.0–100) | 0.046 | 5 | 64.6 (45.3–90.6) | 15 | 85.4 (54.2–100) | 0.097 | |
Parent-report | Swallowing difficulties | 5 | 56.3 (41.7–81.3) | 16 | 87.5 (62.5–100) | 0.011 | 5 | 64.6 (47.9–74.0) | 16 | 90.6 (55.2–100) | 0.013 |
Heartburn | 5 | 62.5 (41.7–81.3) | 16 | 87.5 (56.3–100) | 0.007 | 5 | 55.4 (47.9–80.1) | 16 | 90.1 (64.6–100) | 0.006 | |
Cough | 9 | 65.6 (41.7–81.3) | 13 | 87.5 (75.0–100) | 0.001 | 9 | 69.0 (47.9–80.2) | 13 | 92.7 (64.6–100) | 0.006 | |
Airway infections | 5 | 62.5 (41.7–87.5) | 16 | 84.4 (50.0–100) | 0.072 | 5 | 69.8 (55.4–80.2) | 16 | 90.1 (47.9–100) | 0.090 |