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Table 2 Post-transplant enzyme activity and biomarker results in 6  patients

From: Thirty-year clinical outcomes after haematopoietic stem cell transplantation in neuronopathic Gaucher disease

Patient

 

Follow up results (years’ post-transplant)

Follow up results (years’ post-transplant)

6

Enzyme activity

55% of healthy control (0.5 year)

3.10 nmol/h/mg (20 year)

Chitotriosidase

54 umol/L/h (20 year)

7

Enzyme activity

7.9 nmol/h/mg (6 year)

3.6 nmol/h/mg (21 year)

Chitotriosidase

42 umol/L/h (6 year)

47 umol/L/h (21 year)

8

Enzyme activity

10.2 nmol/h/mg (10 year)

7.6 nmol/h/mg (18 years)

Chitotriosidase

67 nmol/h/ml (10 year)

73 nmol/h/ml (18 years)

9

Enzyme activity

4.9 nmol/mg/h (10 year)

Chitotriosidase

91 umol/L.h (10 year)

1

Enzyme activity

Chitotriosidase

11 nkat/L (30 years)

2

Enzyme activity

Chitotriosidase

14 nkat/L (25 years)

  1. Enzyme activity all measured in peripheral leukocytes—assays varied slightly by laboratory and era but all national reference validated centres
  2. *NR Enzyme activity: 5.4–16.8; Chitotriosidase NR: < 150 nmol/h/mg or < 40 nkat/L