Fig. 4
From: Small fiber involvement is independent from clinical pain in late-onset Pompe disease
Bar chart showing time periods (duration of symptoms to onset of ERT therapy, onset of ERT therapy to biopsy) and patients with reduced (red) and normal (blue) intraepidermal nerve fiber density (IENFD) at time of biopsy (right end of bar). Each patient is represented by a bar, with the sum of the left and right values representing the total time from symptom onset to the time of biopsy. The distribution of patients with reduced fiber density is evenly distributed across the cohort