From: Genetic insight into Birt–Hogg–Dubé syndrome in Indian patients reveals novel mutations at FLCN
Patients (n = 31) | Demography |
---|---|
Mean age ± SD (range in years) | 49 ± 15.4, (18–87) |
Males | 58% (n = 18) |
Females | 41.9% (n = 13) |
Smoking habit (> 10 years) | 22% (n = 7) |
History of tuberculosis | 16% (n = 5) |
BHDS diagnostic criteria | Number of patients* |
---|---|
Patients with lung cysts or PSP | 96% (n = 30) |
Patients with skin fibrofolliculomas | 35% (n = 11) |
Patients with renal cysts/carcinoma (chromophobe) | 9.6% (n = 3) |
Patients having 1st degree relative with similar respiratory phenotype | 64% (n = 20) |
Asymptomatic family members | n = 74 |
---|---|
Mean age ± SD (range in years) | 36 ± 19.8 (7–88) |
Males | 58% (n = 43) |
Females | 41.8% (n = 31) |
Smoking habit (> 10 years) | 1.3% (n = 1) |
History of tuberculosis | 6.75% (n = 5) |
BHDS diagnostic criterion (except respiratory or dermal manifestation) | |
Asymptomatics with renal cysts/carcinoma** | 2.7% (n = 2) |