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Table 2 Odds ratio of COVID-19 mortality risk factors in univariable and multivariable analyses

From: Increased COVID-19 mortality rate in rare disease patients: a retrospective cohort study in participants of the Genomics England 100,000 Genomes project

 

Univariable OR [95% CI]

Multivariable OR [95% CI]

Age (\(\ge\)60)

14.78 [5.31–47.86]

9.95 [3.52–28.17]*

No of comorbidities (\(\ge\)2)

5.46 [2.15–14.77]

2.10 [0.79–5.58]**

Affected by rare diseases

3.47 [1.21–12.18]

1.94 [0.65–5.80]#

Neurology and neurodevelopmental disorders

4.07 [1.61–10.38]

4.22 [1.60–11.08]#

Early onset dystonia

5.28 [0.09–104.83]

26.64 [2.01–352.67]#

Early onset and familial Parkinson’s Disease

10.92 [0.76–157.41]

11.99 [1.25–114.71]#

Intellectual disability

2.70 [0.26–14.71]

8.10 [1.11–59.00]#

  1. *Adjusted by Number of comorbidities \(\ge 2\) and Affected by rare diseases
  2. **Adjusted by Age (\(\ge 60\)) and Affected by rare diseases
  3. #Adjusted by Age (\(\ge 60\)) and Number of comorbidities \(\ge 2\) in individual logistic regression analysis