Table 4 Evaluation of patients with Prader-Willi syndrome during rhGH treatment
From: Recommendations for the diagnosis and management of childhood Prader-Willi syndrome in China
Management monitoring | Â |
|---|---|
Regular clinical assessment of height, weight, growth rate, body composition, pubertal status, scoliosis, IGF-1, thyroid function, and side effects every 3–6 months |  |
OGTT is recommended to be performed if patients with PWS have history of impaired glucose tolerance, obese, or family history of diabetes | Â |
It had better have an ENT assessment and polysomnography within the first 6Â months | Â |
The ENT assessment, polysomnography, and IGF-1 measurement are necessary, if development or worsening of sleep-disordered breathing, snoring, or enlargement of tonsils and adenoids | Â |
If scoliosis is a matter of concern, the X-ray orthopedic assessment can be performed | Â |
Routine measurement of bone age, especially during adolescence | Â |
Monitoring for hypothyroidism | Â |