Table 4 Summary of organ volume by MN at baseline and follow-up, all patients

Liver, median (range)

Baseline

n = 6

n = 68

n = 4

n = 78

   Absolute values

1.4 (0.3–2.1)

2.4 (0.1–10.9)

0.7 (0.6–0.8)

2.2 (0.1–10.9)

Year 1 (month 12)

n = 2^b

n = 40

n = 0

n = 42

   Absolute values

0.9 (0.6, 1.2)

2.4 (0.5–6.2)

–

2.3 (0.5–6.2)

   Change from baseline^c

0.1 (− 0.1, 0.4)

0.0 (− 5.3–1.0)

–

0.0 (− 5.3–1.0)

   % change from baseline^c

63.4 (− 5.3, 132.1)

1.5 (− 50.9–877.5)

–

1.5 (− 50.9–877.5)

Year 2 (month 24)

n = 0

n = 29

n = 0

n = 29

   Absolute values

–

2.7 (0.6–4.7)

2.7 (0.6–4.7)

   Change from baseline^c

–

− 0.1 (− 6.6–2.3)

–

− 0.1 (− 6.6–2.3)

   % change from baseline^c

–

− 3.0 (− 60.0–159.3)

–

− 3.0 (− 60.0–159.3)

Spleen, median (range)

Baseline

n = 4

n = 53

n = 2

n = 59

   Absolute values

9.5 (6.8–18.1)

4.9 (0.6–121.5)

1.8 (1.6, 2.0)

5.3 (0.6–121.5)

Year 1 (month 12)

n = 2^b

n = 33

n = 0

n = 35

   Absolute values

4.5 (1.9, 7.0)

4.9 (1.7–120.0)

–

4.9 (1.7–120.0)

   Change from baseline^c

− 9.7 (− 11.1, − 8.3)

0.0 (− 82.5–42.3)

–

− 0.2 (− 82.5–42.3)

   % change from baseline^c

− 71.1 (− 81.0, − 61.3)

− 0.9 (− 67.9–863.0)

–

− 6.5 (− 81.0–863.0)

Year 2 (month 24)

n = 0

n = 24

n = 0

n = 24

   Absolute values

–

4.2 (0.8–23.4)

4.2 (0.8–23.4)

   Change from baseline^c

–

− 1.0 (− 98.1–4.2)

–

− 1.0 (− 98.1–4.2)

   % change from baseline^c

–

− 25.0 (− 80.7–114.8)

–

− 25.0 (− 80.7–114.8)