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Fig. 4 | Orphanet Journal of Rare Diseases

Fig. 4

From: Systematic estimation of cystic fibrosis prevalence in Chinese and genetic spectrum comparison to Caucasians

Fig. 4

Haplotype comparison between CCGT, EAS and NFE. A Haplotype structure for 1000genome-NFE, 1000genome-EAS and CCGT-WGS cohorts. The shared blocks with tagged SNPs (vertical line) are the intersected regions of these three cohorts. Only haplotype blocks with length larger than 10 kb were remained. Five haplotype blocks in 1000genome-NFE, three blocks in 1000genome-EAS and four blocks in CCGT-WGS cohorts were found, resulting in five shared blocks. B The distribution of haplotype frequency for each shared block in three cohorts. For each shared block, top five high frequency haplotypes were shown in color and the rest were combined as “other” in grey. The Sankey ribbon between each of the adjacent blocks showed the haplotype intersection statistics. For example, in 1000genome-NFE, 100% of the top 1 haplotype in the shared block 1 were accompanied by top 1 haplotype in the shared block 2. C Pie chart for the haplotype frequencies in the three cohorts. The colored chain rectangles indicated the combined haplotype construction of the five shared blocks for the adjacent sector

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