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Table 5 Summary of infections and immunopathology found in patients with MDS reported in the literature; NR = not reported

From: A brief history of MECP2 duplication syndrome: 20-years of clinical understanding

Feature

Males

n/N

Females

n/N

Total

n/N (%)

References

Respiratory infections

–

–

367/498 (74%)

[1,2,3,4, 8,9,10, 12,13,14, 16,17,18,19,20,21,22, 24,25,26,27,28,29,30,31,32, 34,35,36,37,38, 40,41,42,43,44,45,46,47,48, 51,52,53, 55,56,57, 59,60,61,62,63,64, 66,67,68,69,70,71,72,73,74, 76,77,78, 81,82,83,84,85,86]

Pharyngitis

4/46

0/2

4/48 (8%)

[18, 62, 84]

Tonsilitis

4/24

6/12

10/36 (28%)

[18, 43, 62, 74]

Otitis media

–

–

23/77 (30%)

[5, 8, 9, 18, 40, 43, 74, 84, 85]

Urinary tract infections

–

–

14/56 (25%)

[11, 43, 51, 62, 84]

Sepsis

–

–

11/88 (13%)

[1, 5, 59, 62, 64, 68, 84]

Lymphadenopathy

2/8

NR

2/8 (25%)

[1, 64]